Record in detail


General Info

  • lamp_id:L03A000133
  • Name:DEF2_STOCA
  • FullName:Defensin-2
  • Source:Stomoxys calcitrans
  • Mass:7881 Da
  • Sequence Length:70 aa
  • Isoelectric Point:6.5
  • Activity:Antimicrobial
  • Sequence
        MKFFSLFPVIVVVVACLTMRANAAPSAGNEVDHHPDYVDGVEALRQLEPELHGRYKRATCDLLSMWNVNH
  • Function:Antibacterial peptide active mostly against Gram-negative bacteria. Its activity is enhanced by lipopolysaccharide.

Cross-Linking

  •   Cross-linking
  •   1  Database:Uniprot  O16137
  •   2  Database:AMD  DEF2_STOCA

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L03A000133    From 1 To 70 E-value: 2e-38 Score: 149
        MKFFSLFPVIVVVVACLTMRANAAPSAGNEVDHHPDYVDGVEALRQLEPELHGRYKRATCDLLSMWNVNH
  • 2. L03A000132    From 1 To 70 E-value: 1e-37 Score: 146
        MKFFSLFPVILVVVACLTMRANAAPSAGDEVDHHPDYVDGVEALRQLEPELHGRYKRATCDLLSMWNVNH
  • 3. L03A000131    From 1 To 67 E-value: 0.000000000000001 Score: 73.6
        MKFFMVFVVTFCLAVCFVSQSLAIPA---DAANDAHFVDGVQALKEIEPELHGRYKRATCDLLSGTGINH
  • 4. L03A000167    From 33 To 67 E-value: 0.00000000002 Score: 59.3
        KFVDGLHALKTIEPELHGRYKRATCDLLSGTGINH
  • 5. L03A000136    From 1 To 65 E-value: 0.0000008 Score: 44.3
        MKFFVLVAIAFALLACV---AQAQPVS--DVDPIPEDHVLVHEDAHQ-EVLQHSRQKRATCDLLSKWNWNH

Structure

  •   Domains
  •   1  Name:Defensin_invertebrate/fungal    Interpro Link:IPR001542
  •   2  Name:Knot1    Interpro Link:IPR003614
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities

    •     No MICs found on LAMP database

Toxicity

  •   Toxicity

    •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Lehane S.M.,Wu D.,Lehane M.J.,
  •   Title:Midgut-specific immune molecules are produced by the blood-sucking insect Stomoxys calcitrans.
  •   Journal:Proc. Natl. Acad. Sci. U.S.A., 1997, 94, 11502-11507  [MEDLINE:97470996]

Comments

  •   Comments

    •     No comments found on LAMP database



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