Record in detail

lamp_id:L03A000136
Name:DEFI_DROME
FullName:Defensin
Source:Drosophila melanogaster
Mass:10189.7 Da
Sequence Length:92 aa
Isoelectric Point:7.44
Activity:Antimicrobial
Sequence
MKFFVLVAIAFALLACVAQAQPVSDVDPIPEDHVLVHEDAHQEVLQHSRQKRATCDLLSKWNWNHTACAGHCIAKGFKGGYCNDKAVCVCRN
Function:Responsible for the anti Gram-positive activity of immune hemolymph. Expressed in the absence of immune challenge during metamorphosis.

Top similar AMPs on LAMP
1. L03A000136 From 1 To 92 E-value: 0 Score: 192
MKFFVLVAIAFALLACVAQAQPVSDVDPIPEDHVLVHEDAHQEVLQHSRQKRATCDLLSKWNWNHTACAGHCIAKGFKGGYCNDKAVCVCRN
2. L01A002939 From 1 To 40 E-value: 5e-20 Score: 88.2
ATCDLLSKWNWNHTACAGHCIAKGFKGGYCNDKAVCVCRN
3. L03A000131 From 1 To 94 E-value: 7e-19 Score: 84.3
MKFFMVFVVTFCLAVCFVSQSLAIPADAANDAHFVDGVQALKEIEPELHGRYKRATCDLLSGTGINHSACAAHCLLRGNRGGYCNGKGVCVCRN
4. L03A000132 From 1 To 96 E-value: 4e-18 Score: 81.6
MKFFSLFPVILVVVACLTMRANAAPSAGDEVDHHPDYVDGVEALRQLEPELHGRYKRATCDLLSMWNVNHSACAAHCLLLGKSGGRCNDDAVCVCR
5. L12A09191| From 16 To 98 E-value: 7e-17 Score: 77.8
VISAYPSNPVEVEAEDFDAQDPDLQTFQDTFYEVPQVHSRQKRATCDLLSAFGVGHAACAAHCIGHGYRGGYCNSKAVCTCRR

Reference
[1] Lanot R.,Bulet P.,Meister M.,Hoffmann D.,Dimarcq J.-L.,
Title:Characterization and transcriptional profiles of a Drosophila gene encoding an insect defensin. A study in insect immunity.
Journal:Eur. J. Biochem., 1994, 221, 201-209 [MEDLINE:94222062]
[2] Gocayne J.D.,Evans C.A.,Holt R.A.,Celniker S.E.,Adams M.D.,
Title:The genome sequence of Drosophila melanogaster.
Journal:Science, 2000, 287, 2185-2195 [MEDLINE:20196006]
[3] Campbell K.S.,Matthews B.B.,Mungall C.J.,Crosby M.A.,Misra S.,
Title:Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.
Journal:Genome Biol., 2002, 3, 0-0 [MEDLINE:22426069]
[4] Clark A.G.,Lazzaro B.P.,
Title:Molecular population genetics of inducible antibacterial peptide genes in Drosophila melanogaster.
Journal:Mol. Biol. Evol., 2003, 20, 914-923 [MEDLINE:22625906]