Record in detail


General Info

  • lamp_id:L03A000152
  • Name:DFB40_MOUSE
  • FullName:Beta-defensin 40
  • Source:Mus musculus
  • Mass:8616.3 Da
  • Sequence Length:73 aa
  • Isoelectric Point:9.55
  • Activity:Antimicrobial
  • Sequence
        MKISCFLLMIFFLSCFQINPVAVLDTIKCLQGNNNCHIQKCPWFLLQVSTCYKGKGRCCQKRRWFARSHVYHV
  • Function:Has antibacterial activity (By similarity).

Cross-Linking

  •   Cross-linking
  •   1  Database:Uniprot  Q70KL2
  •   2  Database:AMD  BD40_MOUSE
  •   3  Database:DEF  DEF193

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L03A000152    From 1 To 73 E-value: 2e-39 Score: 152
        MKISCFLLMIFFLSCFQINPVAVLDTIKCLQGNNNCHIQKCPWFLLQVSTCYKGKGRCCQKRRWFARSHVYHV
  • 2. L05ADEF342    From 1 To 73 E-value: 9e-28 Score: 113
        MKISCFLMLVLFLSCFQMNSGAGLDTMKCVRGKNNCHMHRCPWFFVLISTCYSGKGSCCQKRRWFTRSHVNNV
  • 3. L01A000720    From 1 To 50 E-value: 4e-26 Score: 108
        LDTIKCLQGNNNCHIQKCPWFLLQVSTCYKGKGRCCQKRRWFARSHVYHV
  • 4. L05ADEF324    From 1 To 61 E-value: 2e-17 Score: 79.3
        MKISCFLLLVLSLSCFQINPFAVLDTRVCIEKRNTCHILQCPLFRDVVGTCFEGIGKCCHK
  • 5. L12A07933|    From 1 To 62 E-value: 7e-17 Score: 77.4
        MKISCFLLLILSLYFFQINQAIGPDTKKCVQRKNACHYFECPWLYYSVGTCYKGKGKCCQKR

Structure

  •   Domains
  •   1  Name:Defensin_beta-typ    Interpro Link:IPR001855
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities

  •     No MICs found on LAMP database

Toxicity

  •   Toxicity

  •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Marquez G.,Martinez-A C.,Albar J.P.,Villares R.,Zaballos A.,
  •   Title:Identification on mouse chromosome 8 of new beta-defensin genes with regionally specific expression in the male reproductive organ.
  •   Journal:J. Biol. Chem., 2004, 279, 12421-12426  [PubMed:14718547]

Comments

  •   Comments

  •     No comments found on LAMP database



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