Record in detail

lamp_id:L03A000153
Name:TAC1_TACTR
FullName:Tachyplesin-1
Source:Tachypleus tridentatus
Mass:9348.7 Da
Sequence Length:77 aa
Isoelectric Point:4.91
Activity:Antimicrobial
Sequence
MKKLVIALCLMMVLAVMVEEAEAKWCFRVCYRGICYRRCRGKRNEVRQYRDRGYDVRAIPEETFFTRQDEDEDDDEE
Function:Significantly inhibits the growth of Gram-negative and Gram-positive bacteria.

Top similar AMPs on LAMP
1. L03A000153 From 1 To 77 E-value: 2e-40 Score: 155
MKKLVIALCLMMVLAVMVEEAEAKWCFRVCYRGICYRRCRGKRNEVRQYRDRGYDVRAIPEETFFTRQDEDEDDDEE
2. L12A07972| From 1 To 68 E-value: 2e-34 Score: 135
MKKLVIALCLMMVLAVMVEEAEARWCFRVCYRGICYRKCRGKRNEVRQYRDRGYDVRAIPDETFFTRQ
3. L03A000352 From 2 To 69 E-value: 2e-34 Score: 135
MKKLVIALCLMMVLAVMVEEAEARWCFRVCYRGICYRKCRGKRNEVRQYRDRGYDVRAIPDETFFTRQ
4. L12A05479| From 1 To 17 E-value: 0.00002 Score: 40
KWCFRVCYRGICYRRCR
5. L01A000144 From 1 To 17 E-value: 0.00002 Score: 40
KWCFRVCYRGICYRRCR

Reference
[1] Muta T.,Tokunaga F.,Miyata T.,Furunaka H.,Nakamura T.,
Title:Tachyplesin, a class of antimicrobial peptide from the hemocytes of the horseshoe crab (Tachypleus tridentatus). Isolation and chemical structure.
Journal:J. Biol. Chem., 1988, 263, 16709-16713 [MEDLINE:89034158]
[2] Tokunaga F.,Yoshikawa K.,Miyata T.,Yoneya T.,Kawano K.,
Title:Antimicrobial peptide, tachyplesin I, isolated from hemocytes of the horseshoe crab (Tachypleus tridentatus). NMR determination of the beta-sheet structure.
Journal:J. Biol. Chem., 1990, 265, 15365-15367 [MEDLINE:90368729]
[3] Iwanaga S.,Tokunaga F.,Toh Y.,Muta T.,Shigenaga T.,
Title:Antimicrobial tachyplesin peptide precursor. cDNA cloning and cellular localization in the horseshoe crab (Tachypleus tridentatus).
Journal:J. Biol. Chem., 1990, 265, 21350-21354 [MEDLINE:91065956]
[4] Funakoshi S.,Otaka A.,Masuda M.,Kuroda M.,Tamamura H.,
Title:A comparative study of the solution structures of tachyplesin I and a novel anti-HIV synthetic peptide, T22 ([Tyr5,12, Lys7]-polyphemusin II), determined by nuclear magnetic resonance.
Journal:Biochim. Biophys. Acta, 1993, 1163, 209-216 [MEDLINE:93257488]
[5] Muta T.,Seki N.,Kawasaki S.,Takayenoki Y.,Shigenaga T.,
Title:Separation of large and small granules from horseshoe crab (Tachypleus tridentatus) hemocytes and characterization of their components.
Journal:J. Biochem., 1993, 114, 307-316 [MEDLINE:94110249]