Record in detail


General Info

  • lamp_id:L03A000159
  • Name:DEF5_RAT
  • FullName:Defensin 5
  • Source:Rattus norvegicus
  • Mass:10241.8 Da
  • Sequence Length:93 aa
  • Isoelectric Point:7.73
  • Activity:Antimicrobial
  • Sequence
        MKKLVLLSALVLLALQVEAEPTPKTDEGTKTDEQPGKEDQVVSVSIEGQGDPAFQDAVLRDLKCFCRRKSCNWGEGIMGICKKRYGSPILCCR
  • Function:Probably contributes to the antimicrobial barrier function of the small intestine.

Cross-Linking

  •   Cross-linking
  •   1  Database:Uniprot  P82106
  •   2  Database:AMD  DEF5_RAT

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L03A000159    From 1 To 93 E-value: 0 Score: 190
        MKKLVLLSALVLLALQVEAEPTPKTDEGTKTDEQPGKEDQVVSVSIEGQGDPAFQDAVLRDLKCFCRRKSCNWGEGIMGICKKRYGSPILCCR
  • 2. L05ADEF375    From 1 To 93 E-value: 4.99997e-41 Score: 157
        MKKLVLLSALVLLALQVQAEPTPKTDEGTKTDEQPGKEDQVVSVSIEGQGDPAFQDAVLRDLKCFCRAKSCNWGEGIMGICNKRYGSLILCCR
  • 3. L05ADEF190    From 1 To 93 E-value: 2e-40 Score: 155
        MKTLVLLSALVLLALQVQAEPTPKTDEGTKTDEQPGKEDQVVSVSIEGQGDPAFQDAVLRDLKCFCRAKSCNWGEGIMGICNKRYGSLILCCR
  • 4. L05ADEF373    From 1 To 93 E-value: 3e-39 Score: 152
        MKTLVLLSALVLLALQVQAEPTPKTDEGTKTDEQPGKEDQVVSVSIEGQGDPAFQDGVLRDLKCFCRAKSCNWGEGIMGICNKRYGMLILCCR
  • 5. L03A000004    From 1 To 85 E-value: 5e-20 Score: 88.2
        ALVLLAFQVQADPIQNTDEETKTEEQPGEEDQAVSVSF---GDPEGTSLQEESLRDLVCYCRSRGCKGRERMNGTCRKGHLLYMLCCR

Structure

  •   Domains
  •   1  Name:Alpha-defensin    Interpro Link:IPR016327
  •   2  Name:Defensin_beta/neutrophil    Interpro Link:IPR006080
  •   3  Name:Defensin_propep    Interpro Link:IPR002366
  •   4  Name:Mammalian_defensins    Interpro Link:IPR006081
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities

    •     No MICs found on LAMP database

Toxicity

  •   Toxicity

    •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Diamond G.,D"Alessio M.,Viera A.,Condon M.R.,
  •   Title:Induction of a rat enteric defensin gene by hemorrhagic shock.
  •   Journal:Infect. Immun., 1999, 67, 4787-4793  [MEDLINE:99386878]

Comments

  •   Comments

    •     No comments found on LAMP database



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