Record in detail
General Info
- lamp_id:L03A000181
- Name:DFA15_MOUSE
- FullName:Alpha-defensin 15
- Source:Mus musculus
- Mass:10502.9 Da
- Sequence Length:93 aa
- Isoelectric Point:5.15
- Activity:Antimicrobial
- Sequence
MKTLVLLSALVLLAFQVQADPIQNTDEETKTEEQPGEDDQAVSVSFGDPEGSSLQEESLRDLVCYCRKRGCKRREHINGTCRKGHLLYMLCCR - Function:Probably contributes to the antimicrobial barrier function of the small bowel mucosa.
Cross-Linking
- Cross-linking
- 1 Database:Uniprot P50713
- 2 Database:AMD DEF15_MOUSE
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L03A000181 From 1 To 93 E-value: 0 Score: 192
MKTLVLLSALVLLAFQVQADPIQNTDEETKTEEQPGEDDQAVSVSFGDPEGSSLQEESLRDLVCYCRKRGCKRREHINGTCRKGHLLYMLCCR - 2. L03A000183 From 1 To 93 E-value: 5.04467e-44 Score: 167
MKTLVLLSALVLLAFQVQADPIQNTDEETKTEEQPGEEDQAVSVSFGDPEGSSLQEESLRDLVCYCRKRGCKRREHMNGTCRKGHLLYMLCCR - 3. L03A000067 From 1 To 81 E-value: 7.9874e-44 Score: 167
LAFQVQADPIQNTDEETKTEEQPGEDDQAVSVSFGDPEGSSLQEESLRDLVCYCRKRGCKRREHMNGTCRKGHLMYTLCCR - 4. L03A000176 From 1 To 93 E-value: 8.96831e-44 Score: 166
MKTLILLSALVLLAFQVQADPIQNTDEETKTEEQPGEDDQAVSVSFGDPEGSSLQEESLRDLVCYCRTRGCKRREHMNGTCRKGHLMYTLCCR - 5. L03A000003 From 1 To 85 E-value: 8.96831e-44 Score: 166
ALVLLAFQVQADPIQNTDEETKTEEQPGEDDQAVSVSFGDPEGSSLQEESLRDLVCYCRTRGCKRRERMNGTCRKGHLMHTLCCR
Activity
- Antibacterial Activities
No MICs found on LAMP database
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Huttner K.M.,Cano-Gauci D.F.,Nosek M.T.,Hsieh M.M.,Ouellette A.J.,
- Title:Mouse Paneth cell defensins: primary structures and antibacterial activities of numerous cryptdin isoforms.
- Journal:Infect. Immun., 1994, 62, 5040-5047 [MEDLINE:95012724]
- [2] Ouellette A.J.,Selsted M.E.,Huttner K.M.,
- Title:Structure and diversity of the murine cryptdin gene family.
- Journal:Genomics, 1994, 19, 448-453 [MEDLINE:94245232]
Comments
- Comments
No comments found on LAMP database