Record in detail

lamp_id:L03A000212
Name:CECA_HYACE
FullName:Cecropin-A
Source:Hyalophora cecropia
Mass:6952.3 Da
Sequence Length:64 aa
Isoelectric Point:10.92
Activity:Antimicrobial
Sequence
MNFSRIFFFVFACLTALAMVNAAPEPKWKLFKKIEKVGQNIRDGIIKAGPAVAVVGQATQIAKG
Function:Cecropins have lytic and antibacterial activity against several Gram-positive and Gram-negative bacteria.

Top similar AMPs on LAMP
1. L03A000212 From 1 To 64 E-value: 2e-32 Score: 129
MNFSRIFFFVFACLTALAMVNAAPEPKWKLFKKIEKVGQNIRDGIIKAGPAVAVVGQATQIAKG
2. L12A08743| From 1 To 64 E-value: 5e-29 Score: 117
MNFSRIFFFTVFACLTALAMVNAAPEPKWKLFKKIEKVGQNIRDGIIKAGPAVAVVGQA-QIAKG
3. L12A06596| From 1 To 64 E-value: 7e-26 Score: 107
MDFSKIFFFVFACFLALSNVSAAPSPKWKIFKKIEKVGRNVRDGIIKAGPAVQVVGQATSIAKG
4. L03A000216 From 1 To 63 E-value: 4e-25 Score: 105
MNFSRILFFVFACFVALASVSAAPEPRWKVFKKIEKVGRNIRDGVIKAGPAIAVVGQAKALGK
5. L03A000215 From 1 To 63 E-value: 3e-24 Score: 102
MNFSRILFFMFACFVALASVSAVPEPRWKVFKKIEKVGRHIRDGVIKAGPAITVVGQATALGK

Reference
[1] Boman H.G.,Bennich H.,Engstroem A.,Hultmark D.,Steiner H.,
Title:Sequence and specificity of two antibacterial proteins involved in insect immunity.
Journal:Nature, 1981, 292, 246-248 [MEDLINE:81245158]
[2] Boman H.G.,Kapur R.,Bennich H.,Engstroem A.,Hultmark D.,
Title:Insect immunity: isolation and structure of cecropin D and four minor antibacterial components from Cecropia pupae.
Journal:Eur. J. Biochem., 1982, 127, 207-217 [MEDLINE:83053366]
[3] Boman H.G.,Xanthopoulos K.G.,Gudmundsson G.H.,Lidholm D.-A.,
Title:Insect immunity: cDNA clones coding for the precursor forms of cecropins A and D, antibacterial proteins from Hyalophora cecropia.
Journal:FEBS Lett., 1987, 226, 8-12 [:]
[4] Bennich H.,Lindeberg G.,Kraulis P.J.,Engstroem A.,Holak T.A.,
Title:The solution conformation of the antibacterial peptide cecropin A: a nuclear magnetic resonance and dynamical simulated annealing study.
Journal:Biochemistry, 1988, 27, 7620-7629 [MEDLINE:89088132]
[5] Boman H.G.,Gan R.,Aasling B.,Lidholm D.-A.,Gudmundsson G.H.,
Title:The cecropin locus. Cloning and expression of a gene cluster encoding three antibacterial peptides in Hyalophora cecropia.
Journal:J. Biol. Chem., 1991, 266, 11510-11517 [MEDLINE:91268009]