Record in detail


General Info

  • lamp_id:L03A000213
  • Name:CECB_HYACE
  • FullName:Cecropin-B
  • Source:Hyalophora cecropia
  • Mass:6750.1 Da
  • Sequence Length:62 aa
  • Isoelectric Point:11.46
  • Activity:Antimicrobial
  • Sequence
        MNFSRIFFFVFALVLALSTVSAAPEPKWKVFKKIEKMGRNIRNGIVKAGPAIAVLGEAKALG
  • Function:Cecropins have lytic and antibacterial activity against several Gram-positive and Gram-negative bacteria.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L03A000213    From 1 To 62 E-value: 3e-30 Score: 122
        MNFSRIFFFVFALVLALSTVSAAPEPKWKVFKKIEKMGRNIRNGIVKAGPAIAVLGEAKALG
  • 2. L12A08746|    From 1 To 62 E-value: 2e-25 Score: 105
        MNFSRIFLFVFACLVAACSVSAAPEPRWKVFKKIEKVGRNIRDGILKAGPAIAVLGEAKALG
  • 3. L12A08751|    From 1 To 62 E-value: 2e-25 Score: 105
        MNFSRVLLFVFACLVALCSVGAAPEPRWKVFKKIEKMGRNVRDGIIKAGPAIAVLGEAKALG
  • 4. L12A07884|    From 1 To 62 E-value: 4e-25 Score: 105
        MKFSRVFLFVFACLVALSAVSAAPEPRWKVFKKIEKMGRNIRDGIVKAGPAIEVLGSAKALG
  • 5. L03A000216    From 1 To 62 E-value: 4e-25 Score: 104
        MNFSRILFFVFACFVALASVSAAPEPRWKVFKKIEKVGRNIRDGVIKAGPAIAVVGQAKALG

Structure

  •   Domains
  •   1  Name:Cecropin    Interpro Link:IPR000875
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities

  •     No MICs found on LAMP database

Toxicity

  •   Toxicity

  •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Boman H.G.,Bennich H.,Engstroem A.,Hultmark D.,Steiner H.,
  •   Title:Sequence and specificity of two antibacterial proteins involved in insect immunity.
  •   Journal:Nature, 1981, 292, 246-248  [MEDLINE:81245158]
  •   [2]  Xanthopoulos K.G.,Lee J.-Y.,Kockum K.,Faye I.,van Hofsten P.,
  •   Title:Molecular cloning, cDNA sequencing, and chemical synthesis of cecropin B from Hyalophora cecropia.
  •   Journal:Proc. Natl. Acad. Sci. U.S.A., 1985, 82, 2240-2243  [MEDLINE:85190472]
  •   [3]  Lee J.-Y.,Kockum K.,von Hofsten P.,Faye I.,Boman H.G.,
  •   Title:On the primary structures of lysozyme, cecropins and attacins from Hyalophora cecropia.
  •   Journal:Dev. Comp. Immunol., 1985, 9, 551-558  [MEDLINE:86005745]
  •   [4]  Faye I.,Kockum K.,Gan R.,Lee J.-Y.,Xanthopoulos G.,
  •   Title:The structure of the gene for cecropin B, an antibacterial immune protein from Hyalophora cecropia.
  •   Journal:Eur. J. Biochem., 1988, 172, 371-376  [MEDLINE:88166708]

Comments

  •   Comments

  •     No comments found on LAMP database



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