Record in detail
General Info
- lamp_id:L03A000213
- Name:CECB_HYACE
- FullName:Cecropin-B
- Source:Hyalophora cecropia
- Mass:6750.1 Da
- Sequence Length:62 aa
- Isoelectric Point:11.46
- Activity:Antimicrobial
- Sequence
MNFSRIFFFVFALVLALSTVSAAPEPKWKVFKKIEKMGRNIRNGIVKAGPAIAVLGEAKALG - Function:Cecropins have lytic and antibacterial activity against several Gram-positive and Gram-negative bacteria.
Cross-Linking
- Cross-linking
- 1 Database:dbAMP dbAMP_08745
- 2 Database:Uniprot P01508
- 3 Database:AMD CECB_HYACE
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L03A000213 From 1 To 62 E-value: 3e-30 Score: 122
MNFSRIFFFVFALVLALSTVSAAPEPKWKVFKKIEKMGRNIRNGIVKAGPAIAVLGEAKALG - 2. L12A08746| From 1 To 62 E-value: 2e-25 Score: 105
MNFSRIFLFVFACLVAACSVSAAPEPRWKVFKKIEKVGRNIRDGILKAGPAIAVLGEAKALG - 3. L12A08751| From 1 To 62 E-value: 2e-25 Score: 105
MNFSRVLLFVFACLVALCSVGAAPEPRWKVFKKIEKMGRNVRDGIIKAGPAIAVLGEAKALG - 4. L12A07884| From 1 To 62 E-value: 4e-25 Score: 105
MKFSRVFLFVFACLVALSAVSAAPEPRWKVFKKIEKMGRNIRDGIVKAGPAIEVLGSAKALG - 5. L03A000216 From 1 To 62 E-value: 4e-25 Score: 104
MNFSRILFFVFACFVALASVSAAPEPRWKVFKKIEKVGRNIRDGVIKAGPAIAVVGQAKALG
Activity
- Antibacterial Activities
No MICs found on LAMP database
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Boman H.G.,Bennich H.,Engstroem A.,Hultmark D.,Steiner H.,
- Title:Sequence and specificity of two antibacterial proteins involved in insect immunity.
- Journal:Nature, 1981, 292, 246-248 [MEDLINE:81245158]
- [2] Xanthopoulos K.G.,Lee J.-Y.,Kockum K.,Faye I.,van Hofsten P.,
- Title:Molecular cloning, cDNA sequencing, and chemical synthesis of cecropin B from Hyalophora cecropia.
- Journal:Proc. Natl. Acad. Sci. U.S.A., 1985, 82, 2240-2243 [MEDLINE:85190472]
- [3] Lee J.-Y.,Kockum K.,von Hofsten P.,Faye I.,Boman H.G.,
- Title:On the primary structures of lysozyme, cecropins and attacins from Hyalophora cecropia.
- Journal:Dev. Comp. Immunol., 1985, 9, 551-558 [MEDLINE:86005745]
- [4] Faye I.,Kockum K.,Gan R.,Lee J.-Y.,Xanthopoulos G.,
- Title:The structure of the gene for cecropin B, an antibacterial immune protein from Hyalophora cecropia.
- Journal:Eur. J. Biochem., 1988, 172, 371-376 [MEDLINE:88166708]
Comments
- Comments
No comments found on LAMP database