Record in detail

lamp_id:L03A000222
Name:CECA_AEDAE
FullName:Cecropin-A
Source:Aedes aegypti
Mass:6150.4 Da
Sequence Length:59 aa
Isoelectric Point:11.31
Activity:Antimicrobial
Sequence
MNFTKLFLLIAVAVLLLTGQSEAGGLKKLGKKLEGAGKRVFNAAEKALPVVAGAKALRK
Function:Antibacterial activity against Gram-negative bacteria E.coli D22 and D31, E.carotovora, K.pneumoniae, P.aeruginosa, S.typhimurium, E.cloacae B12 and X.campestris and Gram-positive bacteria A.viridans, M.luteus, B.megaterium and S.pyogenes. Possesses antifungal activity against F.oxysporum, F.culmorum and N.crassa, C.albicans, C.neoformans and S.cerevisiae. No activity against Gram-negative S.marcescens Db11, Gram-positive B.cereus, B.subtilis, B.thuringiensis, S.aureus and L.monocytogenes, the fungi A.fumigatus and B.bassiana and C.glabrata.

Top similar AMPs on LAMP
1. L03A000222 From 1 To 59 E-value: 1e-26 Score: 109
MNFTKLFLLIAVAVLLLTGQSEAGGLKKLGKKLEGAGKRVFNAAEKALPVVAGAKALRK
2. L12A08733| From 1 To 57 E-value: 3e-19 Score: 85.9
MNFSKIFFIVVLAVLLLCSQTEAGRLKKLGKKIEGAGKRVFKAAEKALPVVAGVKAL
3. L03A000210 From 1 To 57 E-value: 3e-19 Score: 85.9
MNFSKIFIFVVLAVLLLCSQTEAGRLKKLGKKIEGAGKRVFKAAEKALPVVAGVKAL
4. L12A08732| From 1 To 57 E-value: 4e-19 Score: 85.1
MNFSKIFFFVVLAVLLLCSQTEAGRLKKLGKKIEGAGKRVFKAAEKALPVVAGVKAL
5. L12A08739| From 1 To 57 E-value: 5e-19 Score: 84.7
MNFSKIFIFVVLAVVLLCSQTEAGRLKKLGKKIEGAGKRVFKAAEKALPVVAGVKAL

Reference
[1] Richman A.,Kamal S.,Vizioli J.,Charlet M.,Lowenberger C.A.,
Title:Antimicrobial activity spectrum, cDNA cloning and mRNA expression of a newly isolated member of the cecropin family from the mosquito vector Aedes aegypti.
Journal:J. Biol. Chem., 1999, 274, 20092-20097 [MEDLINE:99329007]
[2] Kodira C.D.,Haas B.J.,Lawson D.,Wortman J.R.,Nene V.,
Title:Genome sequence of Aedes aegypti, a major arbovirus vector.
Journal:Science, 2007, 316, 1718-1723 [PubMed:17510324]