Record in detail
General Info
- lamp_id:L03A000227
- Name:STMX_STOCA
- FullName:Stomoxyn
- Source:Stomoxys calcitrans
- Mass:7173.5 Da
- Sequence Length:67 aa
- Isoelectric Point:10.55
- Activity:Antimicrobial
- Sequence
MNFYKYLVVLVVLVLCLSATQTEARGFRKHFNKLVKKVKHTISETAHVAKDTAVIAGSGAAVVAATG - Function:Has antimicrobial activity against most Gram-positive and Gram-negative bacteria, filamentous fungi and yeasts tested. Has trypanolytic effect on T.b.rhodesiense and limited hemolytic activity against bovine red blood cells.
Cross-Linking
- Cross-linking
- 1 Database:dbAMP dbAMP_08774
- 2 Database:Uniprot Q8T9R8
- 3 Database:AMD STOX_STOMA
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L03A000227 From 1 To 67 E-value: 1e-33 Score: 133
MNFYKYLVVLVVLVLCLSATQTEARGFRKHFNKLVKKVKHTISETAHVAKDTAVIAGSGAAVVAATG - 2. L13A022946 From 1 To 33 E-value: 0.00000000000004 Score: 68.2
RGFRKHFNKLVKKVKHTISETAHVAKDTAVIAG - 3. L13A011665 From 1 To 33 E-value: 0.00000000000004 Score: 68.2
RGFRKHFNKLVKKVKHTISETAHVAKDTAVIAG - 4. L13A015838 From 1 To 42 E-value: 0.0000000000003 Score: 65.5
GFRKRFNKLVKKVKHTIKETANVSKDVAIVAGSGVAVGAAMG - 5. L13A026983 From 2 To 43 E-value: 0.0000000000003 Score: 65.5
GFRKRFNKLVKKVKHTIKETANVSKDVAIVAGSGVAVGAAMG
Activity
- Antibacterial Activities
No MICs found on LAMP database
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Brun R.,Vovelle F.,Hamilton J.V.,Munks R.J.L.,Boulanger N.,
- Title:Epithelial innate immunity. A novel antimicrobial peptide with antiparasitic activity in the blood-sucking insect Stomoxys calcitrans.
- Journal:J. Biol. Chem., 2002, 277, 49921-49926 [PubMed:12372834]
- [2] Vovelle F.,Bulet P.,Boulanger N.,Meudal H.,Landon C.,
- Title:Solution structures of stomoxyn and spinigerin, two insect antimicrobial peptides with an alpha-helical conformation.
- Journal:Biopolymers, 2006, 81, 92-103 [PubMed:16170803]
Comments
- Comments
No comments found on LAMP database