Record in detail
General Info
- lamp_id:L03A000238
- Name:D104A_HUMAN
- FullName:Beta-defensin 104
- Source:Homo sapiens
- Mass:8511.9 Da
- Sequence Length:72 aa
- Isoelectric Point:9.4
- Activity:Antimicrobial
- Sequence
MQRLVLLLAVSLLLYQDLPVRSEFELDRICGYGTARCRKKCRSQEYRIGRCPNTYACCLRKWDESLLNRTKP - Function:Has antimicrobial activity. Synergistic effects with lysozyme and DEFB103.
Cross-Linking
- Cross-linking
- 1 Database:Uniprot Q8WTQ1
- 2 Database:AMD BD04_HUMAN
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L03A000238 From 1 To 72 E-value: 7e-38 Score: 147
MQRLVLLLAVSLLLYQDLPVRSEFELDRICGYGTARCRKKCRSQEYRIGRCPNTYACCLRKWDESLLNRTKP - 2. L12A08975| From 1 To 72 E-value: 1e-37 Score: 146
MQRLVLLLAISLLLYQDLPVRSEFELDRICGYGTARCRKKCRSQEYRIGRCPNTYACCLRKWDESLLNRTKP - 3. L12A08978| From 1 To 72 E-value: 8e-35 Score: 137
MQRLVLLLTISVLLYQDIPVRSEFEWDRICGYGTARCRNKCRSQEYRIGRCPNTFACCLRKWDESLLNSTKP - 4. L12A08977| From 1 To 72 E-value: 1e-33 Score: 133
MQRLVLLLTISVLLYQDIPVRSEFEWDRICGYGTARCRNKCQSQEYRIGRCPNTFACCLRKWDESLPNSTKP - 5. L12A08968| From 1 To 72 E-value: 3e-32 Score: 128
MQRFVLLLAISLLLYQDLPVRSEFELDRICGYGTARCRKKCRSQEYRIGRCPNTFACCLRKWDESLLNRTKP
Structure
- Domains
No domains found on LAMP database
- Structures
No structs found on LAMP database
Activity
- Antibacterial Activities
No MICs found on LAMP database
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Kluever E.,Rodriguez-Jimenez F.-J.,Schulz S.,Krause A.,Conejo-Garcia J.-R.,
- Title:Human beta-defensin 4: a novel inducible peptide with a specific salt-sensitive spectrum of antimicrobial activity.
- Journal:FASEB J., 2001, 15, 1819-1821 [PubMed:11481241]
- [2]
- Title:The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
- Journal:Genome Res., 2004, 14, 2121-2127 [PubMed:15489334]
Comments
- Comments
No comments found on LAMP database