Record in detail
General Info
- lamp_id:L03A000241
- Name:DEF1_DERVA
- FullName:Defensin
- Source:Dermacentor variabilis
- Mass:8040.4 Da
- Sequence Length:74 aa
- Isoelectric Point:9.07
- Activity:Antimicrobial
- Sequence
MRGLCICLVFLLVCGLVSATAAAPAESEVAHLRVRRGFGCPLNQGACHNHCRSIRRRGGYCSGIIKQTCTCYRN - Function:Antibacterial activity against Gram-positive and Gram-negative bacteria.
Cross-Linking
- Cross-linking
- 1 Database:dbAMP dbAMP_09021
- 2 Database:Uniprot Q86QI5
- 3 Database:AMD DEF1_DERVA
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L03A000241 From 1 To 74 E-value: 2e-38 Score: 149
MRGLCICLVFLLVCGLVSATAAAPAESEVAHLRVRRGFGCPLNQGACHNHCRSIRRRGGYCSGIIKQTCTCYRN - 2. L12A11860| From 2 To 52 E-value: 2e-25 Score: 105
PAESEAAHLRVRRGFGCPLNQGACHNHCRSIRRRGGYCSGIIKQTCTCYRN - 3. L12A01314| From 1 To 51 E-value: 9e-24 Score: 100
EEESEVAHLRVRRGFGCPLNQGACHRHCRSIRRRGGYCSGIIKQTCTCYRN - 4. L05ADEF394 From 4 To 52 E-value: 1e-21 Score: 93.6
ESDVPHVRVRRGFGCPLNQGACHNHCRSIGRRGGYCAGIIKQTCTCYRK - 5. L05ADEF234 From 1 To 38 E-value: 5e-18 Score: 81.6
GFGCPLNQGACHNHCRSIRRRGGYCSGIIKQTCTCYRN
Structure
- Domains
- 1 Name:Defensin_invertebrate/fungal Interpro Link:IPR001542
- Structures
No structs found on LAMP database
Activity
- Antibacterial Activities
No MICs found on LAMP database
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Hynes W.L.,Sonenshine D.E.,Johns R.,
- Title:Identification of a defensin from the hemolymph of the American dog tick, Dermacentor variabilis.
- Journal:Insect Biochem. Mol. Biol., 2001, 31, 857-865 [MEDLINE:21332638]
- [2] Hynes W.L.,Ratzlaff R.E.,Sonenshine D.E.,Ceraul S.M.,
- Title:An arthropod defensin expressed by the hemocytes of the American dog tick, Dermacentor variabilis (Acari: Ixodidae).
- Journal:Insect Biochem. Mol. Biol., 2003, 33, 1099-1103 [PubMed:14563361]
Comments
- Comments
No comments found on LAMP database