Record in detail
General Info
- lamp_id:L03A000249
- Name:DEFB4_RAT
- FullName:Beta-defensin 4
- Source:Rattus norvegicus
- Mass:6946.3 Da
- Sequence Length:63 aa
- Isoelectric Point:10.1
- Activity:Antimicrobial
- Sequence
MRIHYLLFSFLLVLLSPLSAFTQSINNPITCLTKGGVCWGPCTGGFRQIGTCGLPRVRCCKKK - Function:Has bactericidal activity (By similarity).
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L03A000249 From 1 To 63 E-value: 3e-32 Score: 129
MRIHYLLFSFLLVLLSPLSAFTQSINNPITCLTKGGVCWGPCTGGFRQIGTCGLPRVRCCKKK - 2. L03A000151 From 1 To 63 E-value: 4e-20 Score: 88.2
MKIHYLLFAFILVMLSPLAAFSQLINSPVTCMSYGGSCQRSCNGGFRLGGHCGHPKIRCCRRK - 3. L01A003488 From 1 To 41 E-value: 2e-19 Score: 86.3
QSINNPITCLTKGGVCWGPCTGGFRQIGTCGLPRVRCCKKK - 4. L03A000251 From 1 To 61 E-value: 2e-18 Score: 83.2
MRIHYLLFTFLLVLLSPLAAFTQIINNPITCMTNGAICWGPCPTAFRQIGNCGHFKVRCCK - 5. L03A000243 From 1 To 63 E-value: 3e-16 Score: 75.5
MRIHYLLFAFLLVLLSPPAAFSKKINNPVSCLRKGGRCWNRCIGNTRQIGSCGVPFLKCCKRK
Activity
- Antibacterial Activities
No MICs found on LAMP database
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Mallampali R.K.,Nishimura D.,Barahmand-Pour F.,Mills J.N.,Jia H.P.,
- Title:Molecular cloning and characterization of rat genes encoding homologues of human beta-defensins.
- Journal:Infect. Immun., 1999, 67, 4827-4833 [MEDLINE:99386883]
- [2] Zhang G.,Blecha F.,Sang Y.,Cai Y.,Patil A.A.,
- Title:Cross-species analysis of the mammalian beta-defensin gene family: presence of syntenic gene clusters and preferential expression in the male reproductive tract.
- Journal:Physiol. Genomics, 2005, 23, 5-17 [PubMed:16033865]
Comments
- Comments
No comments found on LAMP database