Record in detail

lamp_id:L03A000250
Name:DEFB8_MOUSE
FullName:Beta-defensin 8
Source:Mus musculus
Mass:6760.1 Da
Sequence Length:60 aa
Isoelectric Point:9.52
Activity:Antimicrobial
Sequence
MRIHYLLFTFLLVLLSPLAAFSQKINEPVSCIRNGGICQYRCIGLRHKIGTCGSPFKCCK
Function:A synthetic peptide displays antimicrobial activities against S.aureus, P.aeruginosa, E.coli and B.cepacia. The antimicrobial activity against S.aureus, E.coli and B.cepacia is reduced in raised concentration of NaCl, but its action against P.aeruginosa is independent of NaCl concentration.

Top similar AMPs on LAMP
1. L03A000250 From 1 To 60 E-value: 1e-30 Score: 123
MRIHYLLFTFLLVLLSPLAAFSQKINEPVSCIRNGGICQYRCIGLRHKIGTCGSPFKCCK
2. L12A09028| From 1 To 60 E-value: 4e-23 Score: 98.2
MRIHYLLFTFLLVLLSPLAAFSQKINDPVTYIRNGGICQYRCIGLRHKIGTCGSPFKCCK
3. L01A003016 From 1 To 35 E-value: 3e-16 Score: 75.5
NEPVSCIRNGGICQYRCIGLRHKIGTCGSPFKCCK
4. L03A000243 From 1 To 61 E-value: 0.00000000000001 Score: 70.1
MRIHYLLFAFLLVLLSPPAAFSKKINNPVSCLRKGGRCWNRCIGNTRQIGSCGVPFLKCCK
5. L03A000151 From 1 To 61 E-value: 0.00000000000002 Score: 69.3
MKIHYLLFAFILVMLSPLAAFSQLINSPVTCMSYGGSCQRSCNGGFRLGGHCGHPKIRCCR

Reference
[1] Dorin J.R.,Cross S.H.,Kilanowski F.M.,Rolfe M.,Morrison G.M.,
Title:
Journal:Mamm. Genome, 2002, 13, 603-603 [DOI:10.1007/s00335-002-0016-2]
[2] Forssmann W.-G.,Conejo-Garcia J.-R.,Kluever E.,Schweimer K.,Bauer F.,
Title:Structure determination of human and murine beta-defensins reveals structural conservation in the absence of significant sequence similarity.
Journal:Protein Sci., 2001, 10, 2470-2479 [MEDLINE:21571984]
[3] Dorin J.R.,Cross S.H.,Kilanowski F.M.,Rolfe M.,Morrison G.M.,
Title:Identification and characterisation a novel murine beta defensin related gene.
Journal:Mamm. Genome, 2002, 13, 445-451 [MEDLINE:22213784]