Record in detail

General Info

lamp_id:L03A000251
Name:DEFB4_MOUSE
FullName:Beta-defensin 4
Source:Mus musculus
Mass:7128.6 Da
Sequence Length:63 aa
Isoelectric Point:9.22
Activity:Antimicrobial
Sequence
MRIHYLLFTFLLVLLSPLAAFTQIINNPITCMTNGAICWGPCPTAFRQIGNCGHFKVRCCKIR
Function:Has bactericidal activity (By similarity).

Cross-Linking

Cross-linking
1 Database:Uniprot P82019
2 Database:AMD BD04_MOUSE

Top similar AMPs

Top similar AMPs on LAMP
1. L03A000251 From 1 To 63 E-value: 5e-33 Score: 130
MRIHYLLFTFLLVLLSPLAAFTQIINNPITCMTNGAICWGPCPTAFRQIGNCGHFKVRCCKIR
2. L01A003010 From 1 To 41 E-value: 3e-20 Score: 89
QIINNPITCMTNGAICWGPCPTAFRQIGNCGHFKVRCCKIR
3. L03A000151 From 1 To 61 E-value: 1e-18 Score: 83.6
MKIHYLLFAFILVMLSPLAAFSQLINSPVTCMSYGGSCQRSCNGGFRLGGHCGHPKIRCCR
4. L03A000249 From 1 To 63 E-value: 4e-18 Score: 82
MRIHYLLFSFLLVLLSPLSAFTQSINNPITCLTKGGVCWGPCTGGFRQIGTCGLPRVRCCKKK
5. L01A003599 From 1 To 41 E-value: 0.000000000002 Score: 62.8
QSINNPVSCVTHGGICWGRCPGSFRQIGTCGLGKVRCCKKK

Structure

Domains
1 Name:Defensin_beta-typ Interpro Link:IPR001855
2 Name:Defensin_beta/neutrophil Interpro Link:IPR006080

Structures

Activity

Antibacterial Activities

Toxicity

Toxicity

Reference

Reference
[1] Vivado A.,Lee S.K.,Schutte B.C.,Wowk S.A.,Jia H.P.,
Title:A novel murine beta-defensin expressed in tongue, esophagus, and trachea.
Journal:J. Biol. Chem., 2000, 275, 33314-33320 [MEDLINE:20517883]
[2] Frith M.C.,Gough J.,Katayama S.,Kasukawa T.,Carninci P.,
Title:The transcriptional landscape of the mammalian genome.
Journal:Science, 2005, 309, 1559-1563 [PubMed:16141072]

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