Record in detail
General Info
- lamp_id:L03A000255
- Name:AMP2_MELGA
- FullName:Antimicrobial peptide THP2
- Source:Meleagris gallopavo
- Mass:7326.7 Da
- Sequence Length:64 aa
- Isoelectric Point:9.62
- Activity:Antimicrobial
- Sequence
MRILYLLFSLLFLALQVSPGLSSPKRDMLFCKRGTCHFGRCPSHLIKVGSCFGFRSCCKWPWDA - Function:Antibacterial activity against the Gram-positive bacterium Staphylococcus aureus. Lacks antibacterial activity against the Gram-negative bacterium E.coli K-12.
Cross-Linking
- Cross-linking
- 1 Database:dbAMP dbAMP_09040
- 2 Database:Uniprot P80392
- 3 Database:AMD BD02_MELGA
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L03A000255 From 1 To 64 E-value: 5e-33 Score: 131
MRILYLLFSLLFLALQVSPGLSSPKRDMLFCKRGTCHFGRCPSHLIKVGSCFGFRSCCKWPWDA - 2. L12A09039| From 1 To 64 E-value: 1e-32 Score: 129
MRILYLLFSLLFLALQVSPGLSSPKRDMLFCKRGSCHFGRCPSHLIKVGSCFGFRSCCKWPWDA - 3. L12A09042| From 1 To 64 E-value: 3e-23 Score: 98.6
MRILYLLFSLLFLALQVSPGLSSPRRDMLFCKGGSCHFGGCPSHLIKVGSCFGFRSCCKWPWNA - 4. L05ADEF300 From 1 To 64 E-value: 8e-23 Score: 97.4
MRILYLLFSLLFLALQASPGLSSPRRDMLFCKGGSCHFGGCPSHLIKVGSCFGFRSCCKWPWNA - 5. L12A09044| From 1 To 64 E-value: 1e-21 Score: 93.6
MRILYLLFSVLFLVLQVSPGLSLPQRDMFLCRKGSCHFGRCPIHLIRVGSCFGFRSCCKSPWDV
Structure
- Domains
- 1 Name:Defensin_beta-typ Interpro Link:IPR001855
- Structures
No structs found on LAMP database
Activity
- Antibacterial Activities
No MICs found on LAMP database
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Harmon B.G.,Wunderlich J.,Beach G.G.,Evans E.W.,
- Title:Isolation of antimicrobial peptides from avian heterophils.
- Journal:J. Leukoc. Biol., 1994, 56, 661-665 [MEDLINE:95053386]
- [2] Jackwood M.W.,Harmon B.G.,Brockus C.W.,
- Title:Characterization of beta-defensin prepropeptide mRNA from chicken and turkey bone marrow.
- Journal:Anim. Genet., 1998, 29, 283-289 [MEDLINE:98418188]
- [3] Lay J.O. Jr.,Liyanage R.,Rath N.C.,Kannan L.,
- Title:Direct screening identifies mature beta-defensin 2 in avian heterophils.
- Journal:Poult. Sci., 2009, 88, 372-379 [PubMed:19151352]
Comments
- Comments
No comments found on LAMP database