Record in detail
General Info
- lamp_id:L03A000262
- Name:DEFB4_BOVIN
- FullName:Beta-defensin 4
- Source:Bos taurus
- Mass:7160.6 Da
- Sequence Length:63 aa
- Isoelectric Point:11.96
- Activity:Antimicrobial
- Sequence
MRLHHLLLAVLFLVLSAGSGFTQRVRNPQSCRWNMGVCIPFLCRVGMRQIGTCFGPRVPCCRR - Function:Has bactericidal activity. Active against E.coli ML35 and S.aureus 502A.
Cross-Linking
- Cross-linking
- 1 Database:dbAMP dbAMP_09084
- 2 Database:Uniprot P46162
- 3 Database:AMD BD04_BOVIN
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L03A000262 From 1 To 63 E-value: 6e-32 Score: 127
MRLHHLLLAVLFLVLSAGSGFTQRVRNPQSCRWNMGVCIPFLCRVGMRQIGTCFGPRVPCCRR - 2. L12A09085| From 1 To 63 E-value: 3e-31 Score: 125
MRLHHLLLAVLFLVLSAGSGFTQRVRNPQSCRWNMGVCIPFWCRVGMRQIGTCFGPRVPCCRR - 3. L12A09083| From 1 To 63 E-value: 3e-25 Score: 105
MRLHHLLLAVLFLDLSAGSGFTQSVRNPQSCRWNMDVCIPFLCRVGMRQIGTCFGPRVPCCRR - 4. L05A0DEF73 From 1 To 43 E-value: 9e-21 Score: 90.5
FTQRVRNPQSCRWNMGVCIPFLCRVGMRQIGTCFGPRVPCCRR - 5. L03A000267 From 1 To 63 E-value: 1e-19 Score: 87
MRLHHLLLVLLFLVLSAGSGFTQVVRNPQSCRWNMGVCIPISCPGNMRQIGTCFGPRVPCCRR
Activity
- Antibacterial Activities
No MICs found on LAMP database
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Novotny M.J.,McGuire P.A.,Morris W.L.,Tang Y.-Q.,Selsted M.E.,
- Title:Purification, primary structures, and antibacterial activities of beta-defensins, a new family of antimicrobial peptides from bovine neutrophils.
- Journal:J. Biol. Chem., 1993, 268, 6641-6648 [MEDLINE:93203264]
Comments
- Comments
No comments found on LAMP database