Record in detail
General Info
- lamp_id:L03A000267
- Name:DEFB5_BOVIN
- FullName:Beta-defensin 5
- Source:Bos taurus
- Mass:7227.7 Da
- Sequence Length:64 aa
- Isoelectric Point:10.53
- Activity:Antimicrobial
- Sequence
MRLHHLLLVLLFLVLSAGSGFTQVVRNPQSCRWNMGVCIPISCPGNMRQIGTCFGPRVPCCRRW - Function:Has bactericidal activity. Active against E.coli ML35 but not against S.aureus 502A.
Cross-Linking
- Cross-linking
- 1 Database:dbAMP dbAMP_09090
- 2 Database:Uniprot P46163
- 3 Database:AMD BD05_BOVIN
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L03A000267 From 1 To 64 E-value: 7e-33 Score: 130
MRLHHLLLVLLFLVLSAGSGFTQVVRNPQSCRWNMGVCIPISCPGNMRQIGTCFGPRVPCCRRW - 2. L12A09083| From 1 To 63 E-value: 2e-21 Score: 92.8
MRLHHLLLAVLFLDLSAGSGFTQSVRNPQSCRWNMDVCIPFLCRVGMRQIGTCFGPRVPCCRR - 3. L02A000040 From 1 To 42 E-value: 2e-20 Score: 89.4
QVVRNPQSCRWNMGVCIPISCPGNMRQIGTCFGPRVPCCRRW - 4. L03A000069 From 1 To 57 E-value: 1e-19 Score: 87
LALLFLVLSAGSGFTQGVRNHVTCRINRGFCVPIRCPGRTRQIGTCFGPRIKCCRSW - 5. L03A000262 From 1 To 63 E-value: 2e-19 Score: 85.9
MRLHHLLLAVLFLVLSAGSGFTQRVRNPQSCRWNMGVCIPFLCRVGMRQIGTCFGPRVPCCRR
Activity
- Antibacterial Activities
No MICs found on LAMP database
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Novotny M.J.,McGuire P.A.,Morris W.L.,Tang Y.-Q.,Selsted M.E.,
- Title:Purification, primary structures, and antibacterial activities of beta-defensins, a new family of antimicrobial peptides from bovine neutrophils.
- Journal:J. Biol. Chem., 1993, 268, 6641-6648 [MEDLINE:93203264]
- [2] Diamond G.,Bhat M.,Rhodes J.,Ryan L.K.,
- Title:Expression of beta-defensin genes in bovine alveolar macrophages.
- Journal:Infect. Immun., 1998, 66, 878-881 [MEDLINE:98114406]
Comments
- Comments
No comments found on LAMP database