Record in detail


General Info

  • lamp_id:L03A000301
  • Name:DMS5_PACDA
  • FullName:Dermaseptin PD-3-7
  • Source:Pachymedusa dacnicolor
  • Mass:7399.3 Da
  • Sequence Length:66 aa
  • Isoelectric Point:4.32
  • Activity:Antimicrobial
  • Sequence
        MSFMKKSLLLVLFLGVVSLSNCEEEKGENENEDHEEHHEEKRLLGDLLGQTSKLVNDLTDTVGSIV
  • Function:Possesses a potent antimicrobial activity against Gram-positive and Gram-negative bacteria. Probably acts by disturbing membrane functions with its amphipathic structure (By similarity).

Cross-Linking

  •   Cross-linking
  •   1  Database:Uniprot  O93455
  •   2  Database:AMD  DMS5_PACDA

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L03A000301    From 1 To 66 E-value: 3e-32 Score: 128
        MSFMKKSLLLVLFLGVVSLSNCEEEKGENENEDHEEHHEEKRLLGDLLGQTSKLVNDLTDTVGSIV
  • 2. L12A06177|    From 1 To 62 E-value: 0.000000002 Score: 52.8
        MAFLKKSLFLVLFLGFVSVSICEEEKRQEDEDEHVEEGENQEEGSEEKRGLLSVLGSVAKHV
  • 3. L12A07237|    From 1 To 63 E-value: 0.00000001 Score: 50.4
        MFTMKKSLLFLFFLGTISLSFCEEERSADEDDEGEMTEEEKRSIRDKIKTTA---IDLAKSAGTGV
  • 4. L12A07344|    From 1 To 54 E-value: 0.00000001 Score: 50.1
        MFTMKKSMLLLFFLGMISLSLCQDERGADEDDGGEMTEEEKRGAFGDFLKGAAK
  • 5. L12A07222|    From 1 To 48 E-value: 0.00000002 Score: 50.1
        MFTMKKPMLLLFFLGTISLSLCQEERGADEDDGGEMTEEEKRGIGSML

Structure

  •   Domains
  •   1  Name:Brevinin    Interpro Link:IPR004275
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities

    •     No MICs found on LAMP database

Toxicity

  •   Toxicity

    •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Wechselberger C.
  •   Title:Cloning of cDNAs encoding new peptides of the dermaseptin-family.
  •   Journal:Biochim. Biophys. Acta, 1998, 1388, 279-283  [MEDLINE:98449786]

Comments

  •   Comments

    •     No comments found on LAMP database



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