Record in detail

lamp_id:L04ABAC022
Name:PLNA_LACPL
FullName:Bacteriocin plantaricin-A
Source:Lactobacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1)
Mass:2683.3 Da
Sequence Length:23 aa
Isoelectric Point:11.02
Activity:Antimicrobial
Sequence
AYSLQMGATAIKQVKKLFKKWGW
Function:This heat stable bacteriocin inhibits the growth of closely related Lactobacillus species. It may act as a pore-forming protein, creating a channel in the cell membrane through a "barrel stave" mechanism.

Top similar AMPs on LAMP
1. L12A07932| From 26 To 48 E-value: 0.00000004 Score: 48.5
AYSLQMGATAIKQVKKLFKKWGW
2. L01A002696 From 4 To 26 E-value: 0.00000005 Score: 48.1
AYSLQMGATAIKQVKKLFKKWGW
3. L04ABAC022 From 1 To 23 E-value: 0.00000007 Score: 47.8
AYSLQMGATAIKQVKKLFKKWGW
4. L01A002697 From 1 To 22 E-value: 0.0000002 Score: 46.2
YSLQMGATAIKQVKKLFKKWGW
5. L01A002698 From 1 To 17 E-value: 0.0002 Score: 35.8
GATAIKQVKKLFKKWGW

Reference
[1] Nes I.F.,Daeschel M.,Sletten K.,Granly Larsen A.G.,Nissen-Meyer J.,
Title:Purification and characterization of plantaricin A, a Lactobacillus plantarum bacteriocin whose activity depends on the action of two peptides.
Journal:J. Gen. Microbiol., 1993, 139, 1973-1978 [MEDLINE:94065628]
[2] Nes F.I.,Nissen-Meyer J.,Havarstein L.S.,Diep B.D.,
Title:The gene encoding plantaricin A, a bacteriocin from Lactobacillus plantarum C11, is located on the same transcription unit as an agr-like regulatory system.
Journal:Appl. Environ. Microbiol., 1994, 60, 160-166 [MEDLINE:94161498]
[3] Nes I.F.,Havarstein L.S.,Diep D.B.,
Title:Characterization of the locus responsible for the bacteriocin production in Lactobacillus plantarum C11.
Journal:J. Bacteriol., 1996, 178, 4472-4483 [MEDLINE:96345611]
[4] Kuipers O.P.,Molenaar D.,van Kranenburg R.,Boekhorst J.,Kleerebezem M.,
Title:Complete genome sequence of Lactobacillus plantarum WCFS1.
Journal:Proc. Natl. Acad. Sci. U.S.A., 2003, 100, 1990-1995 [MEDLINE:22480296]