Record in detail


General Info

  • lamp_id:L05A00DEF4
  • Name:D104A_HUMAN
  • FullName:Beta-defensin 104
  • Source:Homo sapiens
  • Mass:4372.1 Da
  • Sequence Length:37 aa
  • Isoelectric Point:9.47
  • Activity:Antimicrobial
  • Sequence
        ELDRICGYGTARCRKKCRSQEYRIGRCPNTYACCLRK
  • Function:Has antimicrobial activity. Synergistic effects with lysozyme and DEFB103.

Cross-Linking

  •   Cross-linking
  •   1  Database:CAMP  CAMPSQ2
  •   2  Database:DBAASP  490
  •   3  Database:dbAMP  dbAMP_01442
  •   4  Database:SATPdb  satpdb21108
  •   5  Database:Uniprot  Q8WTQ1
  •   6  Database:DEF  DEF4

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L03A000238    From 25 To 61 E-value: 4e-17 Score: 78.6
        ELDRICGYGTARCRKKCRSQEYRIGRCPNTYACCLRK
  • 2. L12A08975|    From 25 To 61 E-value: 4e-17 Score: 78.6
        ELDRICGYGTARCRKKCRSQEYRIGRCPNTYACCLRK
  • 3. L12A09171|    From 25 To 61 E-value: 4e-17 Score: 78.2
        ELDRICGYGTARCRKKCRSQEYRIGRCPNTYACCLRK
  • 4. L12A08968|    From 25 To 61 E-value: 1e-16 Score: 76.6
        ELDRICGYGTARCRKKCRSQEYRIGRCPNTFACCLRK
  • 5. L12A10765|    From 5 To 41 E-value: 1e-16 Score: 76.6
        ELDRICGYGTARCRKKCRSQEYRIGRCPNTYACCLRK

Structure

  •   Domains

  •     No domains found on LAMP database
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities

  •     No MICs found on LAMP database

Toxicity

  •   Toxicity

  •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Kluever E.,Rodriguez-Jimenez F.-J.,Schulz S.,Krause A.,Conejo-Garcia J.-R.,
  •   Title:Human beta-defensin 4: a novel inducible peptide with a specific salt-sensitive spectrum of antimicrobial activity.
  •   Journal:FASEB J., 2001, 15, 1819-1821  [PubMed:11481241]
  •   [2]  
  •   Title:The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
  •   Journal:Genome Res., 2004, 14, 2121-2127  [PubMed:15489334]

Comments

  •   Comments

  •     No comments found on LAMP database



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