Record in detail


General Info

  • lamp_id:L05A00DEF6
  • Name:D105A_HUMAN
  • FullName:Beta-defensin 105
  • Source:Homo sapiens
  • Mass:8922.4 Da
  • Sequence Length:78 aa
  • Isoelectric Point:8.41
  • Activity:Antimicrobial
  • Sequence
        MALIRKTFYFLFAMFFILVQLPSGCQAGLDFSQPFPSGEFAVCESCKLGRGKCRKECLENEKPDGNCRLNFLCCRQRI
  • Function:Has antibacterial activity (Potential).

Cross-Linking

  •   Cross-linking
  •   1  Database:CAMP  CAMPSQ7254
  •   2  Database:dbAMP  dbAMP_06307
  •   3  Database:Uniprot  Q8NG35
  •   4  Database:DEF  DEF6

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L05A00DEF6    From 1 To 78 E-value: 3.00004e-41 Score: 158
        MALIRKTFYFLFAMFFILVQLPSGCQAGLDFSQPFPSGEFAVCESCKLGRGKCRKECLENEKPDGNCRLNFLCCRQRI
  • 2. L12A06323|    From 1 To 78 E-value: 2e-40 Score: 155
        MALNRKTFYFLFAMFFILVQLPSGCQAGLDFSQPFPSGEFAVCESCKLGRGKCRKECLENEKPDGNCRLNFLCCRQRI
  • 3. L12A02448|    From 18 To 95 E-value: 2e-39 Score: 152
        TALIRKTFYFLFAVFFILVQLPSGCQAGLDFSQPFPSGEFAVCESCKLRRGKCRKECLENEKPDGNCRLNFLCCRQRI
  • 4. L12A06308|    From 1 To 78 E-value: 2e-39 Score: 152
        MALIRKTFYFLFAVFFVLVQLPSECQAGLDFSQPFPSGEFAVCESCKLGRGKCRKECLENEKPDGNCRLNFLCCRERI
  • 5. L12A06309|    From 1 To 78 E-value: 7e-38 Score: 147
        MALIRKTFYFVFAVFFILVQQPSGCQAGLEFSEPFPSGKFAVCESCKLGRGKCRKECLENEKPDGSCRLNFLCCRQRV

Structure

  •   Domains

    •     No domains found on LAMP database
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities

    •     No MICs found on LAMP database

Toxicity

  •   Toxicity

    •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Tomita T.,Fukuhara S.,Makita R.,Nagase T.,Yamaguchi Y.,
  •   Title:Identification of multiple novel epididymis-specific beta-defensin isoforms in humans and mice.
  •   Journal:J. Immunol., 2002, 169, 2516-2523  [MEDLINE:22181517]
  •   [2]  Dorin J.R.,Rolfe M.,Semple C.A.M.,
  •   Title:Duplication and selection in the evolution of primate beta-defensin genes.
  •   Journal:Genome Biol., 2003, 4, 0-0  [MEDLINE:22619651]
  •   [3]  
  •   Title:The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
  •   Journal:Genome Res., 2004, 14, 2121-2127  [PubMed:15489334]

Comments

  •   Comments

    •     No comments found on LAMP database



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