Record in detail


General Info

  • lamp_id:L05A0DEF15
  • Name:DB114_HUMAN
  • FullName:Beta-defensin 114
  • Source:Homo sapiens
  • Mass:8317.7 Da
  • Sequence Length:69 aa
  • Isoelectric Point:7.63
  • Activity:Antimicrobial
  • Sequence
        MRIFYYLHFLCYVTFILPATCTLVNADRCTKRYGRCKRDCLESEKQIDICSLPRKICCTEKLYEEDDMF
  • Function:Has antibacterial activity (By similarity).

Cross-Linking

  •   Cross-linking
  •   1  Database:Uniprot  Q8NES9
  •   2  Database:DEF  DEF15

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L05A0DEF15    From 1 To 69 E-value: 3e-36 Score: 141
        MRIFYYLHFLCYVTFILPATCTLVNADRCTKRYGRCKRDCLESEKQIDICSLPRKICCTEKLYEEDDMF
  • 2. L12A11665|    From 2 To 52 E-value: 1e-22 Score: 97.1
        ATCTLVDADRCTKRYGRCKRDCLEIEKQIDICSSPRKICCTERLYEEDDMF
  • 3. L12A07918|    From 1 To 67 E-value: 7e-21 Score: 90.9
        MKIFYYLLHFLCYMTFILPAICTLVDPERCSKMYGQCRTRCYKIEKQIDICYSPSKICCIQRAFEED
  • 4. L01A003688    From 1 To 43 E-value: 4e-20 Score: 88.6
        DRCTKRYGRCKRDCLESEKQIDICSLPRKICCTEKLYEEDDMF
  • 5. L12A01184|    From 1 To 43 E-value: 1e-18 Score: 83.2
        DRCTKRYGHCKRDCLESEKQIDICSSPRKICCTERLYEEDDMF

Structure

  •   Domains

  •     No domains found on LAMP database
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities

  •     No MICs found on LAMP database

Toxicity

  •   Toxicity

  •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Jia H.P.,Walters J.D.,Bartlett J.A.,Mitros J.P.,Schutte B.C.,
  •   Title:Discovery of five conserved beta-defensin gene clusters using a computational search strategy.
  •   Journal:Proc. Natl. Acad. Sci. U.S.A., 2002, 99, 2129-2133  [MEDLINE:21843921]
  •   [2]  Zhang G.,Blecha F.,Sang Y.,Cai Y.,Patil A.A.,
  •   Title:Cross-species analysis of the mammalian beta-defensin gene family: presence of syntenic gene clusters and preferential expression in the male reproductive tract.
  •   Journal:Physiol. Genomics, 2005, 23, 5-17  [PubMed:16033865]

Comments

  •   Comments

  •     No comments found on LAMP database



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