Record in detail


General Info

  • lamp_id:L05A0DEF28
  • Name:DB128_HUMAN
  • FullName:Beta-defensin 128
  • Source:Homo sapiens
  • Mass:10649.6 Da
  • Sequence Length:93 aa
  • Isoelectric Point:9.08
  • Activity:Antimicrobial
  • Sequence
        MKLFLVLIILLFEVLTDGARLKKCFNKVTGYCRKKCKVGERYEIGCLSGKLCCANDEEEKKHVSFKKPHQHSGEKLSVLQDYIILPTITIFTV
  • Function:Has antibacterial activity (Potential).

Cross-Linking

  •   Cross-linking
  •   1  Database:Uniprot  Q7Z7B8
  •   2  Database:DEF  DEF28

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L05A0DEF28    From 1 To 93 E-value: 0 Score: 188
        MKLFLVLIILLFEVLTDGARLKKCFNKVTGYCRKKCKVGERYEIGCLSGKLCCANDEEEKKHVSFKKPHQHSGEKLSVLQDYIILPTITIFTV
  • 2. L01A003720    From 1 To 75 E-value: 3e-40 Score: 155
        ARLKKCFNKVTGYCRKKCKVGERYEIGCLSGKLCCANDEEEKKHVSFKKPHQHSGEKLSVLQDYIILPTITIFTV
  • 3. L12A06063|    From 1 To 88 E-value: 8e-39 Score: 150
        LTLVQCCF-LCTDGARLKKCFNNVTGYCRKKCKVGERYEIGCLSGKLCCINYEEEKEHVSFKKPHQHSGEKLSVQQDYIILPTVTIFTV
  • 4. L01A003665    From 1 To 75 E-value: 5e-38 Score: 147
        ARLKKCFNNITGYCRKKCKVGERYEIGCLSGKLCCVNDEEEKKHVSFKKPHQHSGEKLSVQQDYIILPTITIFAV
  • 5. L12A00524|    From 1 To 75 E-value: 3e-37 Score: 145
        ARLKKCFNNITGYCRKKCKVGERYEIGCLSGKLRCVNDEEEKKHVSFKKPHQHSGEKLSVQQDYIILPTITIFTV

Structure

  •   Domains

  •     No domains found on LAMP database
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities

  •     No MICs found on LAMP database

Toxicity

  •   Toxicity

  •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Gilbert J.G.R.,Burton J.,Ashurst J.L.,Matthews L.H.,Deloukas P.,
  •   Title:The DNA sequence and comparative analysis of human chromosome 20.
  •   Journal:Nature, 2001, 414, 865-871  [MEDLINE:21638749]
  •   [2]  Conejo-Garcia J.-R.,Forssmann W.-G.,Schulz S.,Krause A.,Rodriguez-Jimenez F.-J.,
  •   Title:Distribution of new human beta-defensin genes clustered on chromosome 20 in functionally different segments of epididymis.
  •   Journal:Genomics, 2003, 81, 175-183  [PubMed:12620395]
  •   [3]  
  •   Title:The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
  •   Journal:Genome Res., 2004, 14, 2121-2127  [PubMed:15489334]

Comments

  •   Comments

  •     No comments found on LAMP database



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