Record in detail
General Info
- lamp_id:L05ADEF116
- Name:DAR10_MOUSE
- FullName:Alpha-defensin-related sequence 10
- Source:Mus musculus
- Mass:2822.4 Da
- Sequence Length:26 aa
- Isoelectric Point:8.21
- Activity:Antimicrobial
- Sequence
PPCPSCPSCPWCPMCPRCPSCKCNPK - Function:Apparent precursor of a secreted, cationic, proline- and cysteine-rich peptide that contains Cys-Pro-Xaa repeats. Unlike cryptdin, the proposed mature peptide region lacks the structural motif characteristic of defensins. It may have microbicidal activities (By similarity).
Cross-Linking
- Cross-linking
- 1 Database:DRAMP DRAMP03355
- 2 Database:Uniprot Q64263
- 3 Database:DEF DEF116
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L03A000158 From 66 To 91 E-value: 0.000000001 Score: 53.5
PPCPSCPSCPWCPMCPRCPSCKCNPK - 2. L05ADEF116 From 1 To 26 E-value: 0.00000008 Score: 47.4
PPCPSCPSCPWCPMCPRCPSCKCNPK - 3. L03A000157 From 66 To 91 E-value: 0.0000005 Score: 44.7
PPCPSCLSCPWCPRCLRCPMCKCNPK - 4. L01A002940 From 1 To 26 E-value: 0.00002 Score: 39.7
PPCPSCLSCPWCPRCLRCPMCKCNPK - 5. L01A002941 From 1 To 26 E-value: 0.002 Score: 32.7
PRCPPCPRCSWCPRCPTCPRCNCNPK
Activity
- Antibacterial Activities
No MICs found on LAMP database
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Ouellette A.J.,Huttner K.M.,
- Title:A family of defensin-like genes codes for diverse cysteine-rich peptides in mouse Paneth cells.
- Journal:Genomics, 1994, 24, 99-109 [MEDLINE:95203896]
- [2]
- Title:The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
- Journal:Genome Res., 2004, 14, 2121-2127 [PubMed:15489334]
Comments
- Comments
No comments found on LAMP database