Record in detail

lamp_id:L05ADEF128
Name:DEFL1_CENLL
FullName:Defensin-1
Source:Centruroides limpidus limpidus
Mass:3821.3 Da
Sequence Length:32 aa
Isoelectric Point:8.37
Activity:Antimicrobial
Sequence
ACQFWSCNSSCISRGYRQGYCWGIQYKYCQCQ
Function:Antibacterial protein involved in the immune response to septic injury. When combined with 14.026 kDa and 14.059 kDa hemolymph antimicrobial peptides, it has a strong cooperative activity against the Gram-positive bacteria B.subtilis and S.aureus, and against the Gram-negative bacteria E.coli DH5-alpha and K.pneumoniae ATCC 138833. No detectable antibacterial activity when present alone. Has no hemolytic activity in human erythrocytes.

Top similar AMPs on LAMP
1. L03A000127 From 25 To 56 E-value: 0.00000000000003 Score: 68.9
ACQFWSCNSSCISRGYRQGYCWGIQYKYCQCQ
2. L05ADEF128 From 1 To 32 E-value: 0.0000000000004 Score: 65.5
ACQFWSCNSSCISRGYRQGYCWGIQYKYCQCQ
3. L13A012049 From 17 To 43 E-value: 0.067 Score: 27.7
DCNGECLLRGYKGGYCSGFANVNCWCE
4. L03A000005 From 15 To 39 E-value: 0.089 Score: 27.3
ACAAHCLSKGYRGGYCDG--KKVCNCR
5. L05ADEF403 From 15 To 39 E-value: 0.16 Score: 26.6
ACAAHCLAKGYRGGYCDG--RKVCNCR

Reference
[1] Scaloni A.,Diego-Garcia E.,D"Ambrosio C.,Garcia B.I.,Rodriguez De La Vega R.C.,
Title:Antimicrobial peptide induction in the haemolymph of the Mexican scorpion Centruroides limpidus limpidus in response to septic injury.
Journal:Cell. Mol. Life Sci., 2004, 61, 1507-1519 [PubMed:15197474]