Record in detail


General Info

  • lamp_id:L05ADEF163
  • Name:DFB12_MOUSE
  • FullName:Beta-defensin 12
  • Source:Mus musculus
  • Mass:9657.2 Da
  • Sequence Length:85 aa
  • Isoelectric Point:8.28
  • Activity:Antimicrobial
  • Sequence
        MKNLPSNMALSREVFYFGFALFFIVVELPSGSWAGLEYSQSFPGGEIAVCETCRLGRGKCRRTCIESEKIAGWCKLNFFCCRERI
  • Function:Has antibacterial activity (By similarity).

Cross-Linking

  •   Cross-linking
  •   1  Database:Uniprot  Q8K4N3
  •   2  Database:DEF  DEF163

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L05ADEF163    From 1 To 85 E-value: 1.4013e-45 Score: 173
        MKNLPSNMALSREVFYFGFALFFIVVELPSGSWAGLEYSQSFPGGEIAVCETCRLGRGKCRRTCIESEKIAGWCKLNFFCCRERI
  • 2. L12A06323|    From 1 To 78 E-value: 2e-28 Score: 115
        MALNRKTFYFLFAMFFILVQLPSGCQAGLDFSQPFPSGEFAVCESCKLGRGKCRKECLENEKPDGNCRLNFLCCRQRI
  • 3. L05A00DEF6    From 1 To 78 E-value: 5e-28 Score: 114
        MALIRKTFYFLFAMFFILVQLPSGCQAGLDFSQPFPSGEFAVCESCKLGRGKCRKECLENEKPDGNCRLNFLCCRQRI
  • 4. L12A06308|    From 1 To 78 E-value: 4e-27 Score: 111
        MALIRKTFYFLFAVFFVLVQLPSECQAGLDFSQPFPSGEFAVCESCKLGRGKCRKECLENEKPDGNCRLNFLCCRERI
  • 5. L12A06309|    From 1 To 78 E-value: 2e-26 Score: 109
        MALIRKTFYFVFAVFFILVQQPSGCQAGLEFSEPFPSGKFAVCESCKLGRGKCRKECLENEKPDGSCRLNFLCCRQRV

Structure

  •   Domains

  •     No domains found on LAMP database
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities

  •     No MICs found on LAMP database

Toxicity

  •   Toxicity

  •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Tomita T.,Fukuhara S.,Makita R.,Nagase T.,Yamaguchi Y.,
  •   Title:Identification of multiple novel epididymis-specific beta-defensin isoforms in humans and mice.
  •   Journal:J. Immunol., 2002, 169, 2516-2523  [MEDLINE:22181517]
  •   [2]  Marquez G.,Martinez-A C.,Albar J.P.,Villares R.,Zaballos A.,
  •   Title:Identification on mouse chromosome 8 of new beta-defensin genes with regionally specific expression in the male reproductive organ.
  •   Journal:J. Biol. Chem., 2004, 279, 12421-12426  [PubMed:14718547]
  •   [3]  Frith M.C.,Gough J.,Katayama S.,Kasukawa T.,Carninci P.,
  •   Title:The transcriptional landscape of the mammalian genome.
  •   Journal:Science, 2005, 309, 1559-1563  [PubMed:16141072]

Comments

  •   Comments

  •     No comments found on LAMP database



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