Record in detail


General Info

  • lamp_id:L05ADEF166
  • Name:DFB15_MOUSE
  • FullName:Beta-defensin 15
  • Source:Mus musculus
  • Mass:8730.1 Da
  • Sequence Length:79 aa
  • Isoelectric Point:8.29
  • Activity:Antimicrobial
  • Sequence
        MKTFLFLFAVLFFLDPAKNAFFDEKCSRVNGRCTASCLKNEELVALCQKNLKCCVTVQPCGKSKSNQSDEGSGHMGTWG
  • Function:Has antibacterial activity (By similarity).

Cross-Linking

  •   Cross-linking
  •   1  Database:Uniprot  Q8R2I5
  •   2  Database:DEF  DEF166

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L05ADEF166    From 1 To 79 E-value: 8.99634e-43 Score: 163
        MKTFLFLFAVLFFLDPAKNAFFDEKCSRVNGRCTASCLKNEELVALCQKNLKCCVTVQPCGKSKSNQSDEGSGHMGTWG
  • 2. L01A003012    From 1 To 59 E-value: 7e-31 Score: 124
        FFDEKCSRVNGRCTASCLKNEELVALCQKNLKCCVTVQPCGKSKSNQSDEGSGHMGTWG
  • 3. L05ADEF169    From 23 To 81 E-value: 9e-27 Score: 110
        FFDEKCSRINGRCTASCLKNEELVALCWKNLKCCVTVQSCGRSKGNQSDEGSGHMGTRG
  • 4. L01A002494    From 3 To 61 E-value: 1e-26 Score: 110
        FFDEKCSRINGRCTASCLKNEELVALCWKNLKCCVTVQSCGRSKGNQSDEGSGHMGTRG
  • 5. L01A003647    From 1 To 59 E-value: 5e-23 Score: 97.8
        FFDEKCSRINGRCTESCLKNEELIALCQKNLKCCVTVQPCGRDKGDELDEDSGYNRTRG

Structure

  •   Domains

  •     No domains found on LAMP database
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities

  •     No MICs found on LAMP database

Toxicity

  •   Toxicity

  •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Dorin J.R.,Hill R.E.,Kilanowski F.M.,Semple C.A.M.,Morrison G.M.,
  •   Title:Signal sequence conservation and mature peptide divergence within subgroups of the murine beta-defensin gene family.
  •   Journal:Mol. Biol. Evol., 2003, 20, 460-470  [PubMed:12644567]
  •   [2]  Marquez G.,Martinez-A C.,Albar J.P.,Villares R.,Zaballos A.,
  •   Title:Identification on mouse chromosome 8 of new beta-defensin genes with regionally specific expression in the male reproductive organ.
  •   Journal:J. Biol. Chem., 2004, 279, 12421-12426  [PubMed:14718547]
  •   [3]  Goldstein S.,Zody M.C.,Hillier L.W.,Goodstadt L.,Church D.M.,
  •   Title:Lineage-specific biology revealed by a finished genome assembly of the mouse.
  •   Journal:PLoS Biol., 2009, 7, 0-0  [PubMed:19468303]

Comments

  •   Comments

  •     No comments found on LAMP database



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