Record in detail


General Info

  • lamp_id:L05ADEF184
  • Name:DFB36_MOUSE
  • FullName:Beta-defensin 36
  • Source:Mus musculus
  • Mass:4895.8 Da
  • Sequence Length:43 aa
  • Isoelectric Point:10.06
  • Activity:Antimicrobial
  • Sequence
        MKLLLLTLAALLLVSQLTPGDAQKCWNLHGKCRHRCSRKESVY
  • Function:Has antibacterial activity (By similarity).

Cross-Linking

  •   Cross-linking
  •   1  Database:Uniprot  Q8K3U4
  •   2  Database:DEF  DEF184

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L05ADEF184    From 1 To 43 E-value: 2e-20 Score: 89
        MKLLLLTLAALLLVSQLTPGDAQKCWNLHGKCRHRCSRKESVY
  • 2. L12A08057|    From 1 To 43 E-value: 3e-20 Score: 88.6
        MKLLLLTLAALLLVSQLTPGDAQKCWNLHGKCRHRCSRKESVY
  • 3. L05ADEF340    From 1 To 43 E-value: 0.00000000001 Score: 60.1
        MKLLLLTLAALLLLSQLTPGDAQKCWNLHGKCRHRCSRKESVY
  • 4. L12A08053|    From 1 To 43 E-value: 0.00000000007 Score: 57.8
        MKLLLLTLAALLLLSQLTPGDAQKCWNLNGKCRHRCSRKESVY
  • 5. L12A08073|    From 1 To 43 E-value: 0.0000000003 Score: 55.8
        MKLLSLTLAALLLLSQVTPGSTQKCWNLHGKCRQKCSRKERIY

Structure

  •   Domains

    •     No domains found on LAMP database
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities

    •     No MICs found on LAMP database

Toxicity

  •   Toxicity

    •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Jia H.P.,Walters J.D.,Bartlett J.A.,Mitros J.P.,Schutte B.C.,
  •   Title:Discovery of five conserved beta-defensin gene clusters using a computational search strategy.
  •   Journal:Proc. Natl. Acad. Sci. U.S.A., 2002, 99, 2129-2133  [MEDLINE:21843921]
  •   [2]  Zhang G.,Blecha F.,Sang Y.,Cai Y.,Patil A.A.,
  •   Title:Cross-species analysis of the mammalian beta-defensin gene family: presence of syntenic gene clusters and preferential expression in the male reproductive tract.
  •   Journal:Physiol. Genomics, 2005, 23, 5-17  [PubMed:16033865]
  •   [3]  Frith M.C.,Gough J.,Katayama S.,Kasukawa T.,Carninci P.,
  •   Title:The transcriptional landscape of the mammalian genome.
  •   Journal:Science, 2005, 309, 1559-1563  [PubMed:16141072]
  •   [4]  Goldstein S.,Zody M.C.,Hillier L.W.,Goodstadt L.,Church D.M.,
  •   Title:Lineage-specific biology revealed by a finished genome assembly of the mouse.
  •   Journal:PLoS Biol., 2009, 7, 0-0  [PubMed:19468303]

Comments

  •   Comments

    •     No comments found on LAMP database



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