Record in detail


General Info

  • lamp_id:L05ADEF194
  • Name:DFB41_MOUSE
  • FullName:Beta-defensin 41
  • Source:Mus musculus
  • Mass:7399.7 Da
  • Sequence Length:62 aa
  • Isoelectric Point:8.12
  • Activity:Antimicrobial
  • Sequence
        MKFHLFFFILLFGATILTARSHIDIKNGIERCEKVRGMCKTVCDIDEYDYGYCIRWRNQCCI
  • Function:Has bactericidal activity (By similarity). May play a role in the antimicrobial protection of sperm and urogenital tract epithelia.

Cross-Linking

  •   Cross-linking
  •   1  Database:Uniprot  Q8C1G4
  •   2  Database:DEF  DEF194

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L05ADEF194    From 1 To 62 E-value: 1e-32 Score: 129
        MKFHLFFFILLFGATILTARSHIDIKNGIERCEKVRGMCKTVCDIDEYDYGYCIRWRNQCCI
  • 2. L01A003546    From 1 To 43 E-value: 3e-21 Score: 92
        RSHIDIKNGIERCEKVRGMCKTVCDIDEYDYGYCIRWRNQCCI
  • 3. L05A0DEF11    From 1 To 62 E-value: 2e-20 Score: 89.4
        MKIQLFFFILHFWVTILPARSNFEPKYRFERCEKVRGICKTFCDDVEYDYGYCIKWRSQCCV
  • 4. L12A10774|    From 1 To 45 E-value: 0.0000000000002 Score: 66.2
        RSNFDEKPKYRIERCERVRGFCKTFCDDDEYDYGYCVRWRKQCCI
  • 5. L01A003686    From 1 To 41 E-value: 0.0000000000004 Score: 65.1
        NFDPKYRFERCAKVKGICKTFCDDDEYDYGYCIKWRNQCCI

Structure

  •   Domains

  •     No domains found on LAMP database
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities

  •     No MICs found on LAMP database

Toxicity

  •   Toxicity

  •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Zhang G.,Blecha F.,Sang Y.,Cai Y.,Patil A.A.,
  •   Title:Cross-species analysis of the mammalian beta-defensin gene family: presence of syntenic gene clusters and preferential expression in the male reproductive tract.
  •   Journal:Physiol. Genomics, 2005, 23, 5-17  [PubMed:16033865]
  •   [2]  Poutanen M.,Huhtaniemi I.,Jalkanen J.,
  •   Title:Discovery and characterization of new epididymis-specific beta-defensins in mice.
  •   Journal:Biochim. Biophys. Acta, 2005, 1730, 22-30  [PubMed:16023745]
  •   [3]  Frith M.C.,Gough J.,Katayama S.,Kasukawa T.,Carninci P.,
  •   Title:The transcriptional landscape of the mammalian genome.
  •   Journal:Science, 2005, 309, 1559-1563  [PubMed:16141072]

Comments

  •   Comments

  •     No comments found on LAMP database



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