Record in detail
General Info
- lamp_id:L05ADEF234
- Name:DEF1_DERVA
- FullName:Defensin
- Source:Dermacentor variabilis
- Mass:4231.8 Da
- Sequence Length:38 aa
- Isoelectric Point:9.18
- Activity:Antimicrobial
- Sequence
GFGCPLNQGACHNHCRSIRRRGGYCSGIIKQTCTCYRN - Function:Antibacterial activity against Gram-positive and Gram-negative bacteria.
Cross-Linking
- Cross-linking
- 1 Database:DBAASP 9760
- 2 Database:dbAMP dbAMP_02560
- 3 Database:SATPdb satpdb21822
- 4 Database:Uniprot Q86QI5
- 5 Database:DEF DEF234
- 6 Database:DEF DEF497
- 7 Database:DEF DEF534
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L03A000241 From 37 To 74 E-value: 5e-18 Score: 81.6
GFGCPLNQGACHNHCRSIRRRGGYCSGIIKQTCTCYRN - 2. L12A11860| From 15 To 52 E-value: 9e-18 Score: 80.5
GFGCPLNQGACHNHCRSIRRRGGYCSGIIKQTCTCYRN - 3. L05ADEF234 From 1 To 38 E-value: 3e-17 Score: 79
GFGCPLNQGACHNHCRSIRRRGGYCSGIIKQTCTCYRN - 4. L12A01314| From 14 To 51 E-value: 4e-17 Score: 78.6
GFGCPLNQGACHRHCRSIRRRGGYCSGIIKQTCTCYRN - 5. L12A02558| From 1 To 38 E-value: 2e-16 Score: 76.6
GFGCPLNQGACHNHCRSIKRRGGYCSGIIKQTCTCYRK
Structure
- Domains
- 1 Name:Defensin_invertebrate/fungal Interpro Link:IPR001542
- Structures
No structs found on LAMP database
Activity
- Antibacterial Activities
No MICs found on LAMP database
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Hynes W.L.,Sonenshine D.E.,Johns R.,
- Title:Identification of a defensin from the hemolymph of the American dog tick, Dermacentor variabilis.
- Journal:Insect Biochem. Mol. Biol., 2001, 31, 857-865 [MEDLINE:21332638]
- [2] Hynes W.L.,Ratzlaff R.E.,Sonenshine D.E.,Ceraul S.M.,
- Title:An arthropod defensin expressed by the hemocytes of the American dog tick, Dermacentor variabilis (Acari: Ixodidae).
- Journal:Insect Biochem. Mol. Biol., 2003, 33, 1099-1103 [PubMed:14563361]
Comments
- Comments
No comments found on LAMP database