Record in detail
General Info
- lamp_id:L05ADEF298
- Name:GLL9_CHICK
- FullName:Gallinacin-9
- Source:Gallus gallus
- Mass:7278.4 Da
- Sequence Length:67 aa
- Isoelectric Point:8.38
- Activity:Antimicrobial
- Sequence
MRILFFLVAVLFFLFQAAPAYSQEDADTLACRQSHGSCSFVACRAPSVDIGTCRGGKLKCCKWAPSS - Function:Has bactericidal activity. Potent activity against C.jejuni, C.perfringens, S.aureus, C.albicans and S.cerevisiae. Less potent against S.typhimurium and E.coli.
Cross-Linking
- Cross-linking
- 1 Database:dbAMP dbAMP_09034
- 2 Database:Uniprot Q6QLR1
- 3 Database:DEF DEF298
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L05ADEF298 From 1 To 67 E-value: 4e-35 Score: 138
MRILFFLVAVLFFLFQAAPAYSQEDADTLACRQSHGSCSFVACRAPSVDIGTCRGGKLKCCKWAPSS - 2. L12A09035| From 1 To 67 E-value: 4e-34 Score: 134
MRILFFLVAVLFFLFQAAPAYSQEDPDTLACRQGHGSCSFVACRAPSVDIGTCRGGKLKCCKWAPSS - 3. L12A09032| From 1 To 63 E-value: 5e-28 Score: 114
MRILFFLIAVLFFLFQAAPAYSQADADTIACRQNRGSCSYVACSGPTVDIGTCRTGKLRCCKW - 4. L12A09033| From 1 To 67 E-value: 1e-22 Score: 96.7
MRILFFLVALLFFIFQAAPAYSQGDADTLACRQNRGSCSFIACSGPLVDIGTCRGGKLKCCKWAPSS - 5. L07APD0081 From 1 To 42 E-value: 3e-20 Score: 89
ADTLACRQSHGSCSFVACRAPSVDIGTCRGGKLKCCKWAPSS
Structure
- Domains
- 1 Name:Defensin_beta-typ Interpro Link:IPR001855
- Structures
No structs found on LAMP database
Activity
- Antibacterial Activities
No MICs found on LAMP database
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Cheng J.-F.,Matsuda Y.,Ando J.,Hughes A.L.,Xiao Y.,
- Title:A genome-wide screen identifies a single beta-defensin gene cluster in the chicken: implications for the origin and evolution of mammalian defensins.
- Journal:BMC Genomics, 2004, 5, 56-56 [PubMed:15310403]
- [2] James T.,Tierney J.,Gaines S.,Higgs R.,Lynn D.J.,
- Title:Bioinformatic discovery and initial characterisation of nine novel antimicrobial peptide genes in the chicken.
- Journal:Immunogenetics, 2004, 56, 170-177 [PubMed:15148642]
- [3] Yoshimura Y.,Nishibori M.,Isobe N.,Subedi K.,
- Title:Changes in the expression of gallinacins, antimicrobial peptides, in ovarian follicles during follicular growth and in response to lipopolysaccharide in laying hens (Gallus domesticus).
- Journal:Reproduction, 2007, 133, 127-133 [PubMed:17244739]
- [4] Romijn R.A.,Tjeerdsma-van Bokhoven J.L.M.,Kalkhove S.I.C.,Veldhuizen E.J.A.,van Dijk A.,
- Title:The beta-defensin gallinacin-6 is expressed in the chicken digestive tract and has antimicrobial activity against food-borne pathogens.
- Journal:Antimicrob. Agents Chemother., 2007, 51, 912-922 [PubMed:17194828]
Comments
- Comments
No comments found on LAMP database