Record in detail
General Info
- lamp_id:L05ADEF365
- Name:BDEF_AEQIR
- FullName:Big defensin
- Source:Aequipecten irradians
- Mass:9224.5 Da
- Sequence Length:84 aa
- Isoelectric Point:9.86
- Activity:Antimicrobial
- Sequence
AIPIAYVGMAVAPQVFRWLVRAYGAAAVTAAGVTLRRVINRSRSNDNHSCYGNRGWCRSSCRSYEREYRGGNLGVCGSYKCCVT - Function:Significantly inhibits the growth of Gram-negative and Gram-positive bacteria and fungi in vitro.
Cross-Linking
- Cross-linking
- 1 Database:CAMP CAMPSQ3940
- 2 Database:dbAMP dbAMP_00256
- 3 Database:DRAMP DRAMP03780
- 4 Database:Uniprot Q0H293
- 5 Database:DEF DEF365
- 6 Database:RAP RAPD0069
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L05ADEF365 From 1 To 84 E-value: 9.80909e-45 Score: 169
AIPIAYVGMAVAPQVFRWLVRAYGAAAVTAAGVTLRRVINRSRSNDNHSCYGNRGWCRSSCRSYEREYRGGNLGVCGSYKCCVT - 2. L01A003053 From 4 To 76 E-value: 0.00000000000008 Score: 67.4
IPAIYIGATVGPSVWAYLVALVGAAAVTAANI-------RRASSDNHSCAGNRGWCRSKC--FRHEYVDTYYSAVCGRYFCC - 3. L12A00731| From 5 To 78 E-value: 0.0000000000005 Score: 64.7
AVPLVYMGASVSPAVWNWLLVTFGAAAVAAAAVTV-------SDNDSHSCANNRGWCRSRCFSHEY-IDSWHSDVCGSYDCC - 4. L12A09937| From 15 To 88 E-value: 0.000000000005 Score: 61.6
AIPLVYLGATVSPTVWAWLVGLASAAAVATAGII-------RASSDSHSCANNRGWCRSSCFSHEYIDYY--NSAVCGRYRCC - 5. L12A09939| From 15 To 88 E-value: 0.00000000006 Score: 57.8
AIPLVYWGATVSPTVWAWLV------GLAGAATVATAGIIRA-SSDSHSCANNRGWCRSSCFSHEYIDYY--NSAVCGRYRCC
Structure
- Domains
No domains found on LAMP database
- Structures
No structs found on LAMP database
Activity
- Antibacterial Activities
No MICs found on LAMP database
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Wu L.,Ni D.,Li C.,Song L.,Zhao J.,
- Title:Molecular cloning, expression of a big defensin gene from bay scallop Argopecten irradians and the antimicrobial activity of its recombinant protein.
- Journal:Mol. Immunol., 2007, 44, 360-368 [PubMed:16597463]
Comments
- Comments
No comments found on LAMP database