Record in detail
General Info
- lamp_id:L05ADEF460
- Name:BDEF_VENPH
- FullName:Big defensin
- Source:Venerupis philippinarum
- Mass:1123.2 Da
- Sequence Length:11 aa
- Isoelectric Point:3.75
- Activity:Antimicrobial
- Sequence
AVPDVAFNAYG - Function:Significantly inhibits the growth of Gram-negative and Gram-positive bacteria and fungi in vitro. Has antibacterial activity against S.aureus (MIC=9.6 mg/L), B.subtilis (MIC=76.8 mg/L), M.tetragenus (MIC=38.4 mg/L), E.coli (MIC=76.8 mg/L), V.parahaemolyticus (MIC=19.2 mg/L), and V.anguillarum (MIC=2.1 mg/L).
Cross-Linking
- Cross-linking
- 1 Database:CAMP CAMPSQ3927
- 2 Database:dbAMP dbAMP_00730
- 3 Database:DRAMP DRAMP02397
- 4 Database:SATPdb satpdb11435
- 5 Database:Uniprot P86316
- 6 Database:DEF DEF460
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L05ADEF460 From 1 To 11 E-value: 0.18 Score: 25
AVPDVAFNAYG
Structure
- Domains
No domains found on LAMP database
- Structures
No structs found on LAMP database
Activity
- Antibacterial Activities
No MICs found on LAMP database
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Chen P.-X.,Chen H.-W.,Li R.-G.,Guo D.-S.,Wei Y.-X.,
- Title:Purification of a big defensin from Ruditapes philippinesis and its antibacterial activity.
- Journal:Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao, 2003, 35, 1145-1148 [PubMed:14673509]
Comments
- Comments
No comments found on LAMP database