Record in detail

lamp_id:L06AT00056
Name:THNB_WHEAT
FullName:Purothionin A-1
Source:Triticum aestivum
Mass:4926.8 Da
Sequence Length:45 aa
Isoelectric Point:9.63
Activity:Antimicrobial
Sequence
KSCCKSTLGRNCYNLCRARGAQKLCANVCRCKLTSGLSCPKDFPK
Function:Thionins are small plant proteins which are toxic to animal cells. They seem to exert their toxic effect at the level of the cell membrane. Their precise function is not known.

Top similar AMPs on LAMP
1. L06AT00056 From 1 To 45 E-value: 1e-20 Score: 89.7
KSCCKSTLGRNCYNLCRARGAQKLCANVCRCKLTSGLSCPKDFPK
2. L12A05311| From 1 To 45 E-value: 2e-18 Score: 82.8
KSCCKNTLGRNCYNLCRARGAPKLCSTVCRCKLTSGLSCPKDFPK
3. L13A025115 From 1 To 45 E-value: 3e-18 Score: 82.4
KSCCRSTLGRNCYNLCRARGAQKLCAGVCRCKISSGLSCPKGFPK
4. L06AT00057 From 1 To 45 E-value: 6e-18 Score: 81.3
KSCCRTTLGRNCYNLCRSRGAQKLCSTVCRCKLTSGLSCPKGFPK
5. L06AT00059 From 1 To 45 E-value: 1e-17 Score: 80.1
KSCCRSTLGRNCYNLCRVRGAQKLCANACRCKLTSGLKCPSSFPK

Reference
[1] Yoshizumi H.,Kagamiyama H.,Okada T.,Ohtani S.,
Title:The amino acid sequence of purothionin A, a lethal toxic protein to brewer"s yeast from wheat.
Journal:Agric. Biol. Chem., 1975, 39, 2269-2270 [:]
[2] Jones B.L.,Mak A.S.,
Title:The amino acid sequence of wheat beta-purothionin.
Journal:Can. J. Biochem., 1976, 54, 835-842 [MEDLINE:77046666]
[3] Kagamiyama H.,Yoshizumi H.,Okada T.,Ohtani S.,
Title:Complete primary structures of two subunits of purothionin A, a lethal protein for brewer"s yeast from wheat flour.
Journal:J. Biochem., 1977, 82, 753-767 [MEDLINE:78026451]
[4] Teeter M.M.,Rao U.,Stec B.,
Title:Refinement of purothionins reveals solute particles important for lattice formation and toxicity. Part 2: structure of beta-purothionin at 1.7-A resolution.
Journal:Acta Crystallogr. D, 1995, 51, 914-924 [PubMed:15299761]