Record in detail


General Info

  • lamp_id:L06AT00063
  • Name:THND_HELPU
  • FullName:Hellethionin-D
  • Source:Helleborus purpurascens
  • Mass:4909.5 Da
  • Sequence Length:46 aa
  • Isoelectric Point:8.21
  • Activity:Antimicrobial
  • Sequence
        KSCCRNTLARNCYNACRFTGGSQPTCGILCDCIHVTTTTCPSSHPS
  • Function:Thionins are small plant proteins which are toxic to animal cells. They seem to exert their toxic effect at the level of the cell membrane. Their precise function is not known.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L06AT00063    From 1 To 46 E-value: 8e-22 Score: 94
        KSCCRNTLARNCYNACRFTGGSQPTCGILCDCIHVTTTTCPSSHPS
  • 2. L06AT00078    From 1 To 46 E-value: 0.00000000004 Score: 58.5
        KSCCKNTTGRNCYNACRFAGGSRPVCATACGCKIISGPTCPRDYPK
  • 3. L01A003070    From 1 To 46 E-value: 0.00000000004 Score: 58.5
        KSCCKDTLARNCYNTCRFAGGSRPVCAGACRCKIISGPKCPSDYPK
  • 4. L06AT00065    From 1 To 46 E-value: 0.0000000002 Score: 56.2
        KSCCKNTTGRNCYNACHFAGGSRPVCATACGCKIISGPTCPRDYPK
  • 5. L06AT00064    From 1 To 46 E-value: 0.0000000002 Score: 55.8
        KSCCKDTLARNCYNTCHFAGGSRPVCAGACRCKIISGPKCPSDYPK

Structure

  •   Domains
  •   1  Name:Thionin    Interpro Link:IPR001010
  •   Structures

Activity

  •   Antibacterial Activities

    •     No MICs found on LAMP database

Toxicity

  •   Toxicity

    •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Renner C.,Moroder L.,Kerek F.,Milbradt A.G.,
  •   Title:Structural characterization of hellethionins from Helleborus purpurascens.
  •   Journal:Biochemistry, 2003, 42, 2404-2411  [MEDLINE:22488603]

Comments

  •   Comments

    •     No comments found on LAMP database



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