Record in detail

lamp_id:L07APD0081
Name:GLL9_CHICK
FullName:Gallinacin-9
Source:Gallus gallus
Mass:4359 Da
Sequence Length:42 aa
Isoelectric Point:8.64
Activity:Antimicrobial
Sequence
ADTLACRQSHGSCSFVACRAPSVDIGTCRGGKLKCCKWAPSS
Function:Has bactericidal activity. Potent activity against C.jejuni, C.perfringens, S.aureus, C.albicans and S.cerevisiae. Less potent against S.typhimurium and E.coli.

Top similar AMPs on LAMP
1. L05ADEF298 From 26 To 67 E-value: 3e-20 Score: 89
ADTLACRQSHGSCSFVACRAPSVDIGTCRGGKLKCCKWAPSS
2. L07APD0081 From 1 To 42 E-value: 2e-19 Score: 86.3
ADTLACRQSHGSCSFVACRAPSVDIGTCRGGKLKCCKWAPSS
3. L12A09035| From 27 To 67 E-value: 3e-19 Score: 85.1
DTLACRQGHGSCSFVACRAPSVDIGTCRGGKLKCCKWAPSS
4. L02A001146 From 1 To 41 E-value: 5e-19 Score: 84.7
DTLACRQSHGSCSFVACRAPSVDIGTCRGGKLKCCKWAPSS
5. L02A001548 From 1 To 42 E-value: 8e-19 Score: 84
ADTLACRQSHQSCSFVACRAPSVDIGTCRGGKLKCCKWAPSS

Reference
[1] Cheng J.-F.,Matsuda Y.,Ando J.,Hughes A.L.,Xiao Y.,
Title:A genome-wide screen identifies a single beta-defensin gene cluster in the chicken: implications for the origin and evolution of mammalian defensins.
Journal:BMC Genomics, 2004, 5, 56-56 [PubMed:15310403]
[2] James T.,Tierney J.,Gaines S.,Higgs R.,Lynn D.J.,
Title:Bioinformatic discovery and initial characterisation of nine novel antimicrobial peptide genes in the chicken.
Journal:Immunogenetics, 2004, 56, 170-177 [PubMed:15148642]
[3] Yoshimura Y.,Nishibori M.,Isobe N.,Subedi K.,
Title:Changes in the expression of gallinacins, antimicrobial peptides, in ovarian follicles during follicular growth and in response to lipopolysaccharide in laying hens (Gallus domesticus).
Journal:Reproduction, 2007, 133, 127-133 [PubMed:17244739]
[4] Romijn R.A.,Tjeerdsma-van Bokhoven J.L.M.,Kalkhove S.I.C.,Veldhuizen E.J.A.,van Dijk A.,
Title:The beta-defensin gallinacin-6 is expressed in the chicken digestive tract and has antimicrobial activity against food-borne pathogens.
Journal:Antimicrob. Agents Chemother., 2007, 51, 912-922 [PubMed:17194828]