Record in detail


General Info

  • lamp_id:L11A003198
  • Name:Dermcidin, DCD-1L
  • FullName:
  • Source: Homo sapiens
  • Mass:4747.3 Da
  • Sequence Length:48 aa
  • Isoelectric Point:4.54
  • Activity:Gram+Gram-Fungus
  • Sequence
        SSLLEXGLDGAKKAVGGLGKLGKDAVEDLESVGKGAVHDVKDVLDSVL
  • Function:

Cross-Linking

  •   Cross-linking
  •   1  Database:DBAASP  3198

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L07APD0043    From 1 To 48 E-value: 1e-18 Score: 84
        SSLLEKGLDGAKKAVGGLGKLGKDAVEDLESVGKGAVHDVKDVLDSVL
  • 2. L11A003198    From 1 To 48 E-value: 1e-18 Score: 83.6
        SSLLEXGLDGAKKAVGGLGKLGKDAVEDLESVGKGAVHDVKDVLDSVL
  • 3. L01A000260    From 1 To 47 E-value: 3e-18 Score: 82.4
        SSLLEKGLDGAKKAVGGLGKLGKDAVEDLESVGKGAVHDVKDVLDSV
  • 4. L13A028469    From 1 To 45 E-value: 3e-17 Score: 79
        LEKGLDGAKKAVGGLGKLGKDAVEDLESVGKGAVHDVKDVLDSVL
  • 5. L13A027432    From 1 To 29 E-value: 0.000000008 Score: 50.8
        SSLLEKGLDGAKKAVGGLGKLGKDAVEDL

Structure

  •   Domains

  •     No domains found on LAMP database
  •   Structures

Activity

  •   Antibacterial Activities

  •     No MICs found on LAMP database

Toxicity

  •   Toxicity

  •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Schittek B, Hipfel R, Sauer B, Bauer J, Kalbacher H, Stevanovic S, Schirle M, Schroeder K, Blin n, M
  •   Title:Dermcidin: a novel human antibiotic peptide secreted by sweat glands
  •   Journal:nat Immunol, 2001, 2, 1133-1137  [:11694882]
  •   [2]  Rieg S, Steffen H, Seeber S, Humeny A, Kalbacher H, Dietz K, Garbe C, Schittek B
  •   Title:Deficiency of dermcidin-derived antimicrobial peptides in sweat of patients with atopic dermatitis correlates with an impaired innate defense of human skin in vivo
  •   Journal:J Immunol, 2005, 174, 8003-8010  [:15944307]
  •   [3]  Seny¨¹rek I, Doring G, Kalbacher H, Deeg M, Peschel A, Wolz C, Schittek B
  •   Title:Resistance to dermcidin-derived peptides is independent of bacterial protease activity
  •   Journal:Int J Antimicrob Agents, 2009, 34, 86-90  [:19201578]

Comments

  •   Comments

  •     No comments found on LAMP database



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