Record in detail
General Info
- lamp_id:L11A003198
- Name:Dermcidin, DCD-1L
- FullName:
- Source: Homo sapiens
- Mass:4747.3 Da
- Sequence Length:48 aa
- Isoelectric Point:4.54
- Activity:Gram+Gram-Fungus
- Sequence
SSLLEXGLDGAKKAVGGLGKLGKDAVEDLESVGKGAVHDVKDVLDSVL - Function:
Cross-Linking
- Cross-linking
- 1 Database:DBAASP 3198
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L07APD0043 From 1 To 48 E-value: 1e-18 Score: 84
SSLLEKGLDGAKKAVGGLGKLGKDAVEDLESVGKGAVHDVKDVLDSVL - 2. L11A003198 From 1 To 48 E-value: 1e-18 Score: 83.6
SSLLEXGLDGAKKAVGGLGKLGKDAVEDLESVGKGAVHDVKDVLDSVL - 3. L01A000260 From 1 To 47 E-value: 3e-18 Score: 82.4
SSLLEKGLDGAKKAVGGLGKLGKDAVEDLESVGKGAVHDVKDVLDSV - 4. L13A028469 From 1 To 45 E-value: 3e-17 Score: 79
LEKGLDGAKKAVGGLGKLGKDAVEDLESVGKGAVHDVKDVLDSVL - 5. L13A027432 From 1 To 29 E-value: 0.000000008 Score: 50.8
SSLLEKGLDGAKKAVGGLGKLGKDAVEDL
Activity
- Antibacterial Activities
No MICs found on LAMP database
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Schittek B, Hipfel R, Sauer B, Bauer J, Kalbacher H, Stevanovic S, Schirle M, Schroeder K, Blin n, M
- Title:Dermcidin: a novel human antibiotic peptide secreted by sweat glands
- Journal:nat Immunol, 2001, 2, 1133-1137 [:11694882]
- [2] Rieg S, Steffen H, Seeber S, Humeny A, Kalbacher H, Dietz K, Garbe C, Schittek B
- Title:Deficiency of dermcidin-derived antimicrobial peptides in sweat of patients with atopic dermatitis correlates with an impaired innate defense of human skin in vivo
- Journal:J Immunol, 2005, 174, 8003-8010 [:15944307]
- [3] Seny¨¹rek I, Doring G, Kalbacher H, Deeg M, Peschel A, Wolz C, Schittek B
- Title:Resistance to dermcidin-derived peptides is independent of bacterial protease activity
- Journal:Int J Antimicrob Agents, 2009, 34, 86-90 [:19201578]
Comments
- Comments
No comments found on LAMP database