Record in detail


General Info

  • lamp_id:L11A006093
  • Name:Tyrocidine C
  • FullName:
  • Source: Bacillus aneurinolyticus Bacillus brevis
  • Mass:1309.5 Da
  • Sequence Length:10 aa
  • Isoelectric Point:6.02
  • Activity:Gram+Gram-ParasiteCancerFungusMammalian Cell
  • Sequence
        fPWwNQYVXL
  • Function:

Cross-Linking

  •   Cross-linking
  •   1  Database:DBAASP  6093

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L11A006094    From 1 To 10 E-value: 0.63 Score: 23.1
        FPWWNQYVKL
  • 2. L11A006093    From 1 To 10 E-value: 0.77 Score: 23.1
        FPWWNQYVXL
  • 3. L11A006092    From 1 To 10 E-value: 2.8 Score: 21.2
        FPWFNQYVKL
  • 4. L11A006091    From 1 To 10 E-value: 3.5 Score: 20.8
        FPWFNQYVXL
  • 5. L13A011256    From 4 To 10 E-value: 4.2 Score: 20.4
        FPWWNQY

Structure

  •   Domains

    •     No domains found on LAMP database
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities

    •     No MICs found on LAMP database

Toxicity

  •   Toxicity

    •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Troskie AM, Rautenbach M, Delattin n, Vosloo JA, Dathe M, Cammue BP, Thevissen K
  •   Title:Synergistic activity of the tyrocidines, antimicrobial cyclodecapeptides from Bacillus aneurinolyticus, with amphotericin B and caspofungin against Candida albicans biofilms
  •   Journal:Antimicrob Agents Chemother, 2014, 58, 3697-3707  [:24752256]
  •   [2]  Rautenbach M, Vlok nM, Stander M, Hoppe HC
  •   Title:Inhibition of malaria parasite blood stages by tyrocidines, membrane-active cyclic peptide antibiotics from Bacillus brevis
  •   Journal:Biochim Biophys Acta, 2007, 1768, 1488-1497  [:17462586]
  •   [3]  Rautenbach M, Troskie AM, Vosloo JA, Dathe ME
  •   Title:Antifungal membranolytic activity of the tyrocidines against filamentous plant fungi
  •   Journal:Biochimie, 2016  [:27328781]
  •   [4]  Wenzel M, Rautenbach M, Vosloo JA, Siersma T, Aisenbrey CHM, Zaitseva E, Laubscher WE, Rensburg W, B
  •   Title:The Multifaceted Antibacterial Mechanisms of the Pioneering Peptide Antibiotics Tyrocidine and Gramicidin S
  •   Journal:MBio, 2018, 9, e00802  [:]
  •   [5]  Spathelf BM, Rautenbach M
  •   Title:Anti-listerial activity and structure-activity relationships of the six major tyrocidines, cyclic decapeptides from Bacillus aneurinolyticus
  •   Journal:Bioorg Med Chem, 2009, 17, 5541-5548  [:19586775]

Comments

  •   Comments

    •     No comments found on LAMP database



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