Record in detail


General Info

  • lamp_id:L11A008551
  • Name:A3 Single chain (1-20)AMD
  • FullName:
  • Source:
  • Mass:2407.8 Da
  • Sequence Length:20 aa
  • Isoelectric Point:12.51
  • Activity:Gram+Gram-Mammalian Cell
  • Sequence
        XRPDKPRPYLPRPRPPRPVR
  • Function:

Cross-Linking

  •   Cross-linking
  •   1  Database:DBAASP  8551

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L11A008552    From 2 To 20 E-value: 0.0006 Score: 34.3
        RPDKPRPYLPRPRPPRPVR
  • 2. L11A008551    From 2 To 20 E-value: 0.0006 Score: 34.3
        RPDKPRPYLPRPRPPRPVR
  • 3. L02A000707    From 1 To 19 E-value: 0.0006 Score: 34.3
        RPDKPRPYLPRPRPPRPVR
  • 4. L12A07893|    From 21 To 39 E-value: 2.8 Score: 22.3
        PGKPRPYSPRPTSHPRPIR
  • 5. L03A000010    From 21 To 39 E-value: 2.9 Score: 21.9
        PGKPRPYSPRPTSHPRPIR

Structure

  •   Domains

  •     No domains found on LAMP database
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities

  •     No MICs found on LAMP database

Toxicity

  •   Toxicity

  •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Cassone M, Vogiatzi P, La Montagna R, De Olivier Inacio V, Cudic P, Wade JD, Otvos L Jr
  •   Title:Scope and limitations of the designer proline-rich antibacterial peptide dimer, A3-APO, alone or in synergy with conventional antibiotics
  •   Journal:Peptides, 2008, 29, 1878-1886  [:18721837]
  •   [2]  Tailhades J, Li W, Hossain MA, O'Brien-Simpson nM, Reynolds EC, Otvos L Jr, Separovic F, Wade JD
  •   Title:C-terminal modifications broaden the activity of the proline-rich antimicrobial peptide, Chex1-Arg20
  •   Journal:Aust J Chem, 2015, 68, 1373¨C1378  [:]
  •   [3]  Ostorhazi E, Hoffmann R, Herth n, Wade JD, Kraus Cn, Otvos L Jr
  •   Title:Advantage of a narrow Spectrum Host Defense (Antimicrobial) Peptide Over a Broad Spectrum Analog in Preclinical Drug Development
  •   Journal:Front Chem, 2018, 6, 359  [:30186829]

Comments

  •   Comments

  •     No comments found on LAMP database



CAPTCHA Image   Reload Image
Enter Code*: