Record in detail


General Info

  • lamp_id:L11A010851
  • Name:Phylloseptin-PHa
  • FullName:
  • Source: Pithecopus hypochondrialis
  • Mass:1942.2 Da
  • Sequence Length:19 aa
  • Isoelectric Point:7.55
  • Activity:Gram+Gram-CancerFungusMammalian Cell
  • Sequence
        FLSLIPAAISAVSALANHF
  • Function:

Cross-Linking

  •   Cross-linking
  •   1  Database:DBAASP  10851

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L11A010851    From 1 To 19 E-value: 0.0001 Score: 36.6
        FLSLIPAAISAVSALANHF
  • 2. L11A012626    From 1 To 19 E-value: 0.0003 Score: 35.4
        FLSLIPKAISAVSALANHF
  • 3. L01A003365    From 1 To 19 E-value: 0.0003 Score: 35.4
        FLSLIPAAISAVSALADHF
  • 4. L11A012627    From 1 To 19 E-value: 0.0004 Score: 35
        FLSLIPKAISAISALANHF
  • 5. L11A012381    From 1 To 18 E-value: 0.0005 Score: 34.7
        FLSLIPAAISAVSALANH

Structure

  •   Domains

    •     No domains found on LAMP database
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities

    •     No MICs found on LAMP database

Toxicity

  •   Toxicity

    •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Liu J, Wu Q, Li L, Xi X, Wu D, Zhou M, Chen T, Shaw C, Wang L
  •   Title:Discovery of Phylloseptins that Defense against Gram-Positive Bacteria and Inhibit the Proliferation of the non-Small Cell Lung Cancer Cell Line, from the Skin Secretions of Phyllomedusa Frogs
  •   Journal:Molecules, 2017, 22, E1428  [:28850103]
  •   [2]  Liu Y, Du Q, Ma C, Xi X, Wang L, Zhou M, Burrows JF, Chen T, Wang H
  •   Title:Structure-activity relationship of an antimicrobial peptide, Phylloseptin-PHa: balance of hydrophobicity and charge determines the selectivity of bioactivities
  •   Journal:Drug Des Devel Ther, 2019, 13, 447-458  [:30774309]

Comments

  •   Comments

    •     No comments found on LAMP database



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