Record in detail
- Enzy_Id:EN59495702
Name:ALE1_STACP
FullName:Glycyl-glycine endopeptidase ALE-1,ALE-1
Producer Organism:Staphylococcus capitis
Sequence Length:362
Mass:39350
Isoelectric Point:9.57
Target:S. aureus
Link:O05156 - Function:Lyses staphylococcal cells by hydrolyzing the polyglycine interpeptide bridges of the peptidoglycan.
- Antibacterial Activities
No MICs found on enzybiotics database
- Sequence
- MDTNRKFTLVKSLSIGLGTFLVGSVFLTVNDEASASTKVDAPKVEQEAPAKADAPKVEQE APAKADAPKVEQEAPAKVDAPKVEQEAPAKVDAPKVEQEAPAKADAPKVEQKRTFVREAA QSNHSASWLNNYKKGYGYGPYPLGINGGNHYGVDFFMNVGTPVRAISDGKIVEAGWTNYG GGNEIGLVENDGVHRQWYMHLSKFNVKVGDRVKAGQIIGWSGSTGYSTAPHLHFQRMTNS FSNNTAQDPMPFLKSAGYGSNSTSSSNNNGYKTNKYGTLYKSESASFTANTDIITRLTGP FRSMPQSGVLRKGLTIKYDEVMKQDGHVWVGYNTNSGKRVYLPVRTWNESTGELGPLWGT IK
- Domains
- 1 Name:Dup_hybrid_motif Interpro Link:IPR011055
- 2 Name:Peptidase_M23 Interpro Link:IPR016047
- 3 Name:SH3-like_bac Interpro Link:IPR003646
- 4 Name:SH3_5_bac Interpro Link:IPR013667
- Structures
- 1
1R77Method:X-ray
Chains:A/B=271-362
- Reference
- [1] Ohara M.,Nishida T.,Komatsuzawa H.,Aoki S.,Fujiwara T.,
- Title:Mutation analysis of the histidine residues in the glycylglycine endopeptidase ALE-1.
- Journal:J. Bacteriol.,2005,(187):480-487 [PubMed:15629919]
- [2] Komatsuzawa H.,Ohara M.,Akiyama T.,Fujiwara T.,Sugai M.,
- Title:Purification and molecular characterization of glycylglycine endopeptidase produced by Staphylococcus capitis EPK1.
- Journal:J. Bacteriol.,1997,(179):1193-1202 [MEDLINE:97175547]