Record in detail
- Enzy_Id:EN76583764
Name:LYSC2_ONCMY
FullName:Lysozyme C II
Producer Organism:Oncorhynchus mykiss
Sequence Length:144
Mass:15737
Isoelectric Point:8.57
Target:Gram-positive bacteria
Link:P11941 - Function:Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has antibacterial activity against the Gram positive bacterium P.citreus. Has no antibacterial activity against the Gram negative bacteria E.coli and Y.ruckeri. Does not have hemolytic activity against trout erythrocytes.
- Antibacterial Activities
No MICs found on enzybiotics database
- Sequence
- MRAVVVLLLVAVASAKVYDRCELARALKASGMDGYAGNSLPNWVCLSKWESSYNTQATNR NTDGSTDYGIFQINSRYWCDDGRTPGAKNVCGIRCSQLLTADLTVAIRCAKRVVLDPNGI GAWVAWRLHCQNQDLRSYVAGCGV
- Domains
- 1 Name:Glyco_hydro_22 Interpro Link:IPR001916
- 2 Name:Glyco_hydro_22_CS Interpro Link:IPR019799
- 3 Name:Glyco_hydro_22_lys Interpro Link:IPR000974
- 4 Name:Lysozyme-like_dom Interpro Link:IPR023346
- Structures
- 1
1BB6Method:X-ray
Chains:A=16-144 - 2
1BB7Method:X-ray
Chains:A=16-144 - 3
1LMCMethod:X-ray
Chains:A=16-144 - 4
1LMNMethod:X-ray
Chains:A=16-144 - 5
1LMOMethod:X-ray
Chains:A=16-144 - 6
1LMPMethod:X-ray
Chains:A=16-144 - 7
1LMQMethod:X-ray
Chains:A=16-144
- Reference
- [1] Smith V.J.,Kemp G.D.,Fernandes J.M.O.,
- Title:Two novel muramidases from skin mucosa of rainbow trout (Oncorhynchus mykiss).
- Journal:Comp. Biochem. Physiol.,2004,(138):53-64 [PubMed:15142536]
- [2] Wall R.J.,Rexroad C.E. III,Wells K.D.,Foster-Frey J.,Mitra A.,
- Title:Molecular characterization of lysozyme type II gene from rainbow trout (Oncorhynchus mykiss): an evidence of a duplicate gene.
- Journal:Anim. Biotechnol.,2003,(14):7-12 [PubMed:12887175]
- [3] Karlsen S.,Hough E.,Vollan V.B.,
- Title:Structural studies on the binding of 4-methylumbelliferone glycosides of chitin to rainbow trout lysozyme.
- Journal:Acta Crystallogr. D,1999,(55):60-66 [MEDLINE:99190830]
- [4] Riise B.W.,Larsen R.L.,Hansen L.K.,Eliassen B.E.,Karlsen S.,
- Title:Refined crystal structure of lysozyme from the rainbow trout (Oncorhynchus mykiss).
- Journal:Acta Crystallogr. D,1995,(51):354-367 [PubMed:15299303]
- [5] Pakdel F.,Jolles J.,Pham-Dinh D.,Prager E.M.,Dautingny A.,
- Title:cDNA and amino acid sequences of rainbow trout (Oncorhynchus mykiss) lysozymes and their implications for the evolution of lysozyme and lactalbumin.
- Journal:J. Mol. Evol.,1991,(32):187-198 [MEDLINE:91178823]
- [6] Jolles P.,Jolles J.,Grinde B.,
- Title:Purification and characterization of two lysozymes from rainbow trout (Salmo gairdneri).
- Journal:Eur. J. Biochem.,1988,(173):269-273 [MEDLINE:88196109]